RTKN
| Gene Symbol | RTKN |
|---|---|
| Entrez Gene | 6242 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | rhotekin |
| Other Description | - |
| Swissprots | Q96PT6 Q9HB05 Q8WVN1 H7BXD4 Q9BST9 |
| Accessions | EAW99674 EAW99675 EAW99676 Q9BST9 AF049227 AAL16767 AF290512 AAG01181 AK307302 AK308519 AK310036 AW410753 BC004558 AAH04558 BC017727 AAH17727 BG470092 BQ574374 BQ721791 DQ891471 ABM82397 EU176596 ABW03397 XM_005264478 XP_005264535 XM_005264479 XP_005264536 XR_939704 XR_939705 XR_939706 NM_001015055 NP_001015055 NM_001015056 NP_001015056 NM_033046 NP_149035 |
| Function | Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:15480428, ECO:0000269|PubMed:16007136}. |
| Tissue Specificity | Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines. {ECO:0000269|PubMed:10873388, ECO:0000269|PubMed:15480428}. |
Rhotekin CRISPR/Cas9 KO Plasmid (h) - sc-404766 from Santa Cruz Biotechnology
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Rhotekin HDR Plasmid (h) - sc-404766-HDR from Santa Cruz Biotechnology
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Rhotekin Double Nickase Plasmid (h) - sc-404766-NIC from Santa Cruz Biotechnology
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Rhotekin Double Nickase Plasmid (h2) - sc-404766-NIC-2 from Santa Cruz Biotechnology
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Rhotekin CRISPR Activation Plasmid (h) - sc-404766-ACT from Santa Cruz Biotechnology
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Rhotekin CRISPR Activation Plasmid (h2) - sc-404766-ACT-2 from Santa Cruz Biotechnology
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Rhotekin Lentiviral Activation Particles (h) - sc-404766-LAC from Santa Cruz Biotechnology
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Rhotekin Lentiviral Activation Particles (h2) - sc-404766-LAC-2 from Santa Cruz Biotechnology
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Rhotekin siRNA (h) - sc-39223 from Santa Cruz Biotechnology
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Rhotekin shRNA Plasmid (h) - sc-39223-SH from Santa Cruz Biotechnology
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Rhotekin shRNA (h) Lentiviral Particles - sc-39223-V from Santa Cruz Biotechnology
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RTKN RNAi - H00006242-R01 from Novus Biologicals
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RTKN RNAi - H00006242-R02 from Novus Biologicals
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RTKN RNAi - H00006242-R03 from Novus Biologicals
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MISSION® esiRNA - EHU076371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18731 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03022 from Sigma-Aldrich
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RTKN siRNA (Human) - CRH4205 from Cohesion Biosciences
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RTKN - MBS8236942 from MyBioSource
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shRNA set against Human RTKN (NM_033046.2) - SHH400476 from Creative biogene
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shRNA set against Human RTKN(NM_001015056.1) - SHR200434 from Creative biogene
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shRNA set against Human RTKN(NM_001015055.1) - SHR200488 from Creative biogene
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shRNA set against Human RTKN(NM_033046.2) - SHR200506 from Creative biogene
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RTKN shRNA Plasmid (Human) - CHH4205 from Cohesion Biosciences
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