ALKBH2

Gene Symbol	ALKBH2
Entrez Gene	121642
Alt Symbol	ABH2
Species	Human
Gene Type	protein-coding
Description	alkB, alkylation repair homolog 2 (E. coli)
Other Description	2OG-Fe(II) oxy DC1|DNA oxidative demethylase ALKBH2|alkylated DNA repair protein alkB homolog 2|alpha-ketoglutarate-dependent dioxygenase alkB homolog 2|oxy DC1
Swissprots	Q6NS38 A4PET2 Q5XLE3
Accessions	CAG17897 CCQ43124 EAW97845 Q6NS38 AB277859 BAF56576 AI278638 AK309062 AY754389 AAV28301 BC070489 AAH70489 BM785502 BM790974 BM820131 BU623121 CN421655 DA182735 HQ447536 ADQ32022 XM_005253835 XP_005253892 XM_005253836 XP_005253893 NM_001001655 NP_001001655 NM_001145374 NP_001138846 NM_001145375 NP_001138847 NM_001205179 NP_001192108 NM_001205180 NP_001192109
Function	Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1- ethenoadenine (in vitro). Has strong preference for double- stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:18432238, ECO:0000269|PubMed:18519673}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517}. Note=Detected in replication foci during S-phase.
Tissue Specificity	Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ALKBH2-cDNA-Clone - DC08876 from Abgent, a WuXi AppTec company Prices $352.35 Sizes 10 µg Species Human Accession BC070489

ALKBH2 - MBS1271596 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC070489

Human ALKBH2 cDNA clone(NM_001145374.1) - CDFH000674 from Creative Biomart Species Human Accession NM_001145374.1

Human ALKBH2 cDNA clone(NM_001145375.1) - CDFH000675 from Creative Biomart Species Human Accession NM_001145375.1

Human ALKBH2 ORF Clone(NM_001001655.2) - CDCL153642 from Creative Biomart Species Human Accession NM_001001655.2

Human ALKBH2 ORF Clone(NM_001145374.1) - CDCR352776 from Creative Biomart Species Human Accession NM_001145374.1

Human ALKBH2 ORF Clone(NM_001145374.1) - CDCR352777 from Creative Biomart Species Human Accession NM_001145374.1

Human ALKBH2 ORF Clone(NM_001145375.1) - CDCR352778 from Creative Biomart Species Human Accession NM_001145375.1

Human ALKBH2 ORF Clone(NM_001145375.1) - CDCR352779 from Creative Biomart Species Human Accession NM_001145375.1

Human ABH2/ALKBH2 Gene ORF cDNA clone in cloning vector - HG15413-G from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15413-NF from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15413-ACR from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15413-ANR from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15413-NY from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15413-ACG from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15413-CF from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15413-NM from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15413-CM from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15413-NH from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15413-CH from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid - HG15413-UT from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15413-CY from Sino Biological Species Human

Human ABH2/ALKBH2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15413-ANG from Sino Biological Species Human

Human ALKBH2 ORF Clone(NM_001145374.1) - CDCR352776 from Creative biogene Species Human

Human ALKBH2 ORF Clone(NM_001145375.1) - CDCR352778 from Creative biogene Species Human

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