CALD1

Gene Symbol	CALD1
Entrez Gene	800
Alt Symbol	CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22
Species	Human
Gene Type	protein-coding
Description	caldesmon 1
Other Description	caldesmon
Swissprots	Q13979 Q14742 Q9UD91 Q05682 Q14741 Q13978 A8K0X1
Accessions	CAJ29926 EAW83826 EAW83827 EAW83828 EAW83830 EAW83831 EAW83832 EAW83833 EAW83834 EAW83835 Q05682 AB062484 BAB93509 AF247820 AAF69498 AF315788 AI926727 AJ223812 AK021691 AK022222 AK022456 AK289686 BAF82375 AK298524 BAG60727 AK300282 BAH13250 AK304729 BAG65492 AL601004 AU134367 BC005006 AAH05006 BC014035 AAH14035 BC015839 BC040354 AAH40354 BC061926 AAH61926 BF675655 BF965359 BQ010124 BU683034 BX538339 CAD98104 BX648808 BX649088 CAI46261 CA433571 CA447404 CD359921 CK821334 CN314587 CV573441 D90452 BAA14418 D90453 BAA14419 DA323544 DA546174 DB090561 M64110 AAA35636 M83216 AAA58419 XM_006716136 XP_006716199 XM_006716139 XP_006716202 XM_011516585 XP_011514887 XR_927534 XR_927535 XR_927536 XR_927537 XR_927538 XR_927539 XR_927540 XR_927541 XR_927542 NM_004342 NP_004333 NM_033138 NP_149129 NM_033139 NP_149130 NM_033140 NP_149131 NM_033157 NP_149347
Function	Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril {ECO:0000250}. Note=On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). {ECO:0000250}.
Tissue Specificity	High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular- weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart.
Top Pathways	Vascular smooth muscle contraction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Caldesmon full length protein - ab114302 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

Human Caldesmon peptide - ab86635 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

CALD1 / Caldesmon Antibody Blocking Peptide - LS-E8328 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALD1 / Caldesmon Antibody Blocking Peptide - LS-E15723 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALD1 / Caldesmon Antibody Blocking Peptide - LS-E15722 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Caldesmon/CALD1 Protein - H00000800-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CALD1-Antibody-Center-Blocking-Peptide - BP6609c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Caldesmon 1 Blocking Peptide - 33R-3075 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Caldesmon 1 Blocking Peptide - 33R-9647 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Caldesmon Protein - abx065663 from Abbexa Category Protein Source E.coli Species Human

Caldesmon - H00000800-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Caldesmon - H00000800-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CALD1 fusion protein - ag13676 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human CALD1 - CALD1-26059TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Caldesmon (CALD) - RPB324Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Caldesmon (CALD) - RPB324Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Caldesmon (S783) Peptide - BS1437P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Caldesmon (CALD) - RPB324Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Caldesmon(CALD1) - CSB-YP004441HU CSB-EP004441HU CSB-BP004441HU CSB-MP004441HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Caldesmon (CALD) - RPU140576 from Biomatik Category Protein Prices $220.00, $440.00, $660.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Caldesmon (transcript variant 3) - TP323989 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Caldesmon, Recombinant Protein - MBS2029354 from MyBioSource Category Protein Prices $175.00, $360.00, $560.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Caldesmon (CALD1), Recombinant Protein - MBS958308 from MyBioSource Category Protein Prices $1,610.00, $1,610.00, $1,840.00, $1,840.00, $2,770.00, $2,770.00, $3,235.00, $3,235.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Caldesmon/CALD1 Recombinant Protein Antigen - NBP1-85702PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Caldesmon/CALD1 Recombinant Protein Antigen - NBP1-85701PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Search more