MYL12A

Gene Symbol MYL12A
Entrez Gene 10627
Alt Symbol HEL-S-24, MLC-2B, MLCB, MRCL3, MRLC3, MYL2B
Species Human
Gene Type protein-coding
Description myosin, light chain 12A, regulatory, non-sarcomeric
Other Description epididymis secretory protein Li 24|myosin RLC|myosin regulatory light chain 12A|myosin regulatory light chain 2, nonsarcomeric|myosin regulatory light chain 3|myosin regulatory light chain MRLC3|myosin, light polypeptide, regulatory, non-sarcomeric (20kD)
Swissprots D3DUH6 Q13182 Q7Z5Z4 Q53X45 P19105 O14950
Accessions EAX01678 EAX01679 EAX01680 EAX01681 P19105 AK222569 BAD96289 AK291145 BAF83834 AW958488 BC016372 AAH16372 BC031972 AAH31972 BC032748 AAH32748 BM561281 BU615599 CA309747 CD702288 D82059 BAB88919 DQ185044 ABD14424 DQ892814 ABM83740 DQ896060 ABM87059 EU794621 ACJ13675 X54304 CAA38201 XM_005258078 XP_005258135 NM_001303047 NP_001289976 NM_001303048 NP_001289977 NM_001303049 NP_001289978 NM_006471 NP_006462
Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitously expressed in various hematopoietic cells. {ECO:0000269|PubMed:11436981, ECO:0000269|PubMed:18480596}.
Top Pathways Tight junction, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton

MRCL3 CRISPR/Cas9 KO Plasmid (h) - sc-417853 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 HDR Plasmid (h) - sc-417853-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 Double Nickase Plasmid (h) - sc-417853-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 Double Nickase Plasmid (h2) - sc-417853-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 CRISPR Activation Plasmid (h) - sc-417853-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 CRISPR Activation Plasmid (h2) - sc-417853-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 Lentiviral Activation Particles (h) - sc-417853-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 Lentiviral Activation Particles (h2) - sc-417853-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRCL3 siRNA (h) - sc-106238 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRCL3 shRNA Plasmid (h) - sc-106238-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRCL3 shRNA (h) Lentiviral Particles - sc-106238-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRCL3 RNAi - H00010627-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106811 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14828 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14828 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02588 from Sigma-Aldrich

Category miRNA

MYL12A siRNA (Human) - CRH7238 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MYL12A (NM_006471.2) - SHH347892 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MRCL3(NM_006471.2) - SHH197885 from Creative biogene

Category siRNA
Species Reactivities Human

Human MYL12A siRNA - orb267740 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MYL12A shRNA Plasmid (Human) - CHH7238 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MYL12A miRNA 3'UTR clone - MiUTR1H-06412 from Creative biogene

Species Reactivities Human
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