Gene Symbol | GGCT |
---|---|
Entrez Gene | 79017 |
Alt Symbol | C7orf24, CRF21, GCTG, GGC |
Species | Human |
Gene Type | protein-coding |
Description | gamma-glutamylcyclotransferase |
Other Description | cytochrome c-releasing factor 21|gamma -glutamyl cyclotransferase |
Swissprots | Q9BS37 B8ZZR8 O75223 B8ZZN4 B2RDN0 |
Accessions | EAL24452 EAW93950 EAW93951 EAW93952 EAW93953 O75223 AK021779 BAG51049 AK315608 BAG37977 BC000625 AAH00625 BC005356 AAH05356 BC013937 AAH13937 BC019243 AAH19243 BE407390 BE885397 BG527593 HQ448710 ADQ33188 NM_001199815 NP_001186744 NM_001199816 NP_001186745 NM_001199817 NP_001186746 NM_024051 NP_076956 NR_037669 |
Function | Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. {ECO:0000269|PubMed:16765912, ECO:0000269|PubMed:18515354}. |
Top Pathways | Glutathione metabolism |