| Gene Symbol |
HRSP12
|
| Entrez Gene |
10247
|
| Alt Symbol |
P14.5, PSP, UK114
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heat-responsive protein 12
|
| Other Description |
14.5 kDa translational inhibitor protein|UK114 antigen homolog|perchloric acid-soluble protein|ribonuclease UK114|translational inhibitor p14.5|translational inhibitor protein p14.5
|
| Swissprots |
Q6IBG0 Q6FHU9 P52758
|
| Accessions |
AAK01939 CAJ42760 EAW91774 EAW91775 P52758 BC010280 AAH10280 BC012592 AAH12592 BC093059 AAH93059 BX348173 CR456844 CAG33125 CR541652 CAG46453 D62115 DQ892797 ABM83723 DQ896044 ABM87043 X95384 CAA64670 NM_005836 NP_005827
|
| Function |
Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Nucleus. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.
|
| Tissue Specificity |
Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues.
|
