Gene Symbol | HRSP12 |
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Entrez Gene | 10247 |
Alt Symbol | P14.5, PSP, UK114 |
Species | Human |
Gene Type | protein-coding |
Description | heat-responsive protein 12 |
Other Description | 14.5 kDa translational inhibitor protein|UK114 antigen homolog|perchloric acid-soluble protein|ribonuclease UK114|translational inhibitor p14.5|translational inhibitor protein p14.5 |
Swissprots | Q6IBG0 Q6FHU9 P52758 |
Accessions | AAK01939 CAJ42760 EAW91774 EAW91775 P52758 BC010280 AAH10280 BC012592 AAH12592 BC093059 AAH93059 BX348173 CR456844 CAG33125 CR541652 CAG46453 D62115 DQ892797 ABM83723 DQ896044 ABM87043 X95384 CAA64670 NM_005836 NP_005827 |
Function | Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear. |
Tissue Specificity | Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues. |
HRSP12 CRISPR/Cas9 KO Plasmid (h) - sc-411443 from Santa Cruz Biotechnology
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HRSP12 HDR Plasmid (h) - sc-411443-HDR from Santa Cruz Biotechnology
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HRSP12 Double Nickase Plasmid (h) - sc-411443-NIC from Santa Cruz Biotechnology
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HRSP12 Double Nickase Plasmid (h2) - sc-411443-NIC-2 from Santa Cruz Biotechnology
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HRSP12 CRISPR Activation Plasmid (h) - sc-411443-ACT from Santa Cruz Biotechnology
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HRSP12 CRISPR Activation Plasmid (h2) - sc-411443-ACT-2 from Santa Cruz Biotechnology
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HRSP12 Lentiviral Activation Particles (h) - sc-411443-LAC from Santa Cruz Biotechnology
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HRSP12 Lentiviral Activation Particles (h2) - sc-411443-LAC-2 from Santa Cruz Biotechnology
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HRSP12 siRNA (h) - sc-77741 from Santa Cruz Biotechnology
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HRSP12 shRNA Plasmid (h) - sc-77741-SH from Santa Cruz Biotechnology
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HRSP12 shRNA (h) Lentiviral Particles - sc-77741-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10303 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10303 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03992 from Sigma-Aldrich
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HRSP12 siRNA (Human) - CRH6934 from Cohesion Biosciences
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HRSP12 RNAi - H00010247-R01 from Novus Biologicals
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HRSP12 - MBS8233708 from MyBioSource
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shRNA set against Human HR (NM_005836.2) - SHH314757 from Creative biogene
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shRNA set against Human HRSP12(NM_005836.2) - SHH131465 from Creative biogene
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Human HRSP12 siRNA - orb267436 from Biorbyt
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HRSP12 shRNA Plasmid (Human) - CHH6934 from Cohesion Biosciences
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HRSP12 miRNA 3'UTR clone - MiUTR1H-04699 from Creative biogene
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