CPQ

Gene Symbol CPQ
Entrez Gene 10404
Alt Symbol LDP, PGCP
Species Human
Gene Type protein-coding
Description carboxypeptidase Q
Other Description Ser-Met dipeptidase|aminopeptidase|blood plasma glutamate carboxypeptidase|lysosomal dipeptidase
Swissprots B2RD88 Q9UNM8 Q9Y646 Q8NBZ1 Q9Y5X6
Accessions EAW91757 EAW91758 Q9Y646 AA492294 AF107833 AAD43213 AF107834 AAD43214 AF119386 AAD31418 AK075132 BAC11423 AK296013 BAG58784 AK304008 BAG64924 AK315447 BAG37835 BC012019 BC020689 AAH20689 BF445505 DA699663 DQ893177 ABM84103 DQ896759 ABM87758 XM_005250755 XP_005250812 XM_006716498 XP_006716561 XM_011516793 XP_011515095 XM_011516794 XP_011515096 XR_428374 XR_928286 NM_016134 NP_057218
Function Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:10206990}. Golgi apparatus {ECO:0000269|PubMed:10206990}. Lysosome {ECO:0000250}. Secreted {ECO:0000269|PubMed:10206990}. Note=Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin. {ECO:0000250}.
Tissue Specificity Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). {ECO:0000269|PubMed:10206990}.

PGCP CRISPR/Cas9 KO Plasmid (h) - sc-411466 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP HDR Plasmid (h) - sc-411466-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP Double Nickase Plasmid (h) - sc-411466-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP Double Nickase Plasmid (h2) - sc-411466-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP CRISPR Activation Plasmid (h) - sc-411466-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP CRISPR Activation Plasmid (h2) - sc-411466-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP Lentiviral Activation Particles (h) - sc-411466-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP Lentiviral Activation Particles (h2) - sc-411466-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGCP siRNA (h) - sc-77755 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGCP shRNA Plasmid (h) - sc-77755-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGCP shRNA (h) Lentiviral Particles - sc-77755-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16681 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16681 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03400 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03400

CPQ siRNA (Human) - CRH7053 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CPQ - MBS8200913 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PGCP (NM_016134.2) - SHH374196 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PGCP(NM_016134.2) - SHR108696 from Creative biogene

Category siRNA
Species Reactivities Human

Human CPQ siRNA - orb267555 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CPQ shRNA Plasmid (Human) - CHH7053 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CPQ miRNA 3'UTR clone - MiUTR1H-07818 from Creative biogene

Species Reactivities Human
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