Gene Symbol | PLA2G1B |
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Entrez Gene | 5319 |
Alt Symbol | PLA2, PLA2A, PPLA2 |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group IB (pancreas) |
Other Description | phosphatidylcholine 2-acylhydrolase 1B|phospholipase A2 |
Swissprots | B2R4H5 Q3KPI1 P04054 |
Accessions | AAA60107 AAB95635 AAR05441 EAW98184 P04054 AA844927 AK311830 BAG34772 BC005386 AAH05386 BC013384 BC106725 AAI06726 BC106726 AAI06727 BE969737 BX113838 CA867923 EU832774 ACE87785 GQ129318 ACT64452 M21054 AAA36450 NM_000928 NP_000919 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. {ECO:0000269|PubMed:19297324}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19297324}. Note=secreted from pancreatic acinar cells in its inactive form. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
PLA2G1B (D1T4C) Rabbit mAb - 14635 from Cell Signaling Technology
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PLA2G1B Antibody - 8962 from Cell Signaling Technology
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group IB sPLA 2 (P-13) - sc-168045 from Santa Cruz Biotechnology
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Anti-PLA2G1B antibody - ab103872 from Abcam
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Anti-PLA2G1B antibody - ab55645 from Abcam
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Anti-PLA2G1B antibody - ab135169 from Abcam
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Anti-PLA2G1B antibody [EPR5186] - ab110706 from Abcam
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Anti-PLA2G1B Antibody - LS-C17271 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (Biotin) - LS-C147617 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C147616 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C147618 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (Internal) - LS-C153410 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa1-148, clone 11n151) - LS-C184869 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C185157 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa134-148) - LS-C55295 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C185158 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (Biotin) - LS-C185159 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C155200 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa116-145, AP) - LS-C266450 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa116-145, APC) - LS-C266451 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa116-145, FITC) - LS-C266452 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa116-145, Azide-free, HRP) - LS-C266453 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa116-145, PE) - LS-C266455 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody (aa110-140) - LS-C324082 from LifeSpan Bioscience
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Anti-PLA2G1B Antibody - LS-C340708 from LifeSpan Bioscience
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