Gene Symbol | PLA2G1B |
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Entrez Gene | 5319 |
Alt Symbol | PLA2, PLA2A, PPLA2 |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group IB (pancreas) |
Other Description | phosphatidylcholine 2-acylhydrolase 1B|phospholipase A2 |
Swissprots | B2R4H5 Q3KPI1 P04054 |
Accessions | AAA60107 AAB95635 AAR05441 EAW98184 P04054 AA844927 AK311830 BAG34772 BC005386 AAH05386 BC013384 BC106725 AAI06726 BC106726 AAI06727 BE969737 BX113838 CA867923 EU832774 ACE87785 GQ129318 ACT64452 M21054 AAA36450 NM_000928 NP_000919 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. {ECO:0000269|PubMed:19297324}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19297324}. Note=secreted from pancreatic acinar cells in its inactive form. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
PLA2G1B-Over-expression-Lysate - LY10739a from Abgent, a WuXi AppTec company
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PLA2G1B 293T Cell Transient Overexpression Lysate(Denatured) - H00005319-T01 from Acris Antibodies
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PLA2G1B overexpression lysate - LY400342 from Acris Antibodies
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PLA2G1B 293 Cell Lysate - 400372 from ABBIOTEC
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PLA2G1B Overexpression Lysate (Native) - NBL1-14471 from Novus Biologicals
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PLA2G1B Over-expression Lysate Product - GWB-89D088 from Genway Biotech
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Human PLA2G1B / PLA2 HEK293 Cell Lysate (WB positive control) - 10865-H08HL-300 from Sino Biological
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PLA2G1B Overexpression Lysate (Denatured) - H00005319-T01 from Novus Biologicals
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Human PLA2G1B Human Cells Transfected Lysate (positive control) (denatured) - orb173551 from Biorbyt
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Panoply™ Human PLA2G1B Knockdown Stable Cell Line - CSC-DC011864 from Creative biogene
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