Gene Symbol | BLOC1S4 |
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Entrez Gene | 55330 |
Alt Symbol | BCAS4L, BLOS4, CNO |
Species | Human |
Gene Type | protein-coding |
Description | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino |
Other Description | BLOC-1 subunit 4|biogenesis of lysosome-related organelles complex 1 subunit 4|cappuccino homolog|protein cappuccino homolog |
Swissprots | Q6NVY6 Q96G84 Q9NUP1 |
Accessions | EAW82382 Q9NUP1 AF085849 AI679712 AK002092 BAA92080 BC001818 BC009890 BC067815 AAH67815 NM_018366 NP_060836 |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:17182842}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Cappuccino (C-13) - sc-46823 from Santa Cruz Biotechnology
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Cappuccino (K-15) - sc-46824 from Santa Cruz Biotechnology
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Anti-CNO antibody - ab55038 from Abcam
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Anti-CNO antibody - ab180078 from Abcam
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Anti-CNO Antibody (aa108-218, Azide-free) - LS-C330364 from LifeSpan Bioscience
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Anti-CNO Antibody (aa114-143) - LS-C203970 from LifeSpan Bioscience
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Anti-CNO Antibody (clone 6C3) - LS-C105154 from LifeSpan Bioscience
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CNO Antibody (6C3) - H00055330-M02 from Novus Biologicals
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CNO Antibody - NBP1-91798 from Novus Biologicals
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CNO Antibody (6C3) - H00055330-M02A from Novus Biologicals
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Monoclonal Anti-CNO antibody produced in mouse - WH0055330M2 from Sigma-Aldrich
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Anti-CNO antibody produced in rabbit - HPA043840 from Sigma-Aldrich
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CNO-Antibody-monoclonal-M02 - AT1570a from Abgent, a WuXi AppTec company
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CNO-Antibody-Center - AP20464c from Abgent, a WuXi AppTec company
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BLOC1S4 Antibody - middle region (OAAB17987) - OAAB17987 from Aviva Systems Biology
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Anti -CNO (Protein Cappuccino Homolog, Biogenesis of Lysosome-related Organelles Complex 1Subunit 4, BLOC-1 Subunit 4, BLOC1S4, FLJ11230) - 125133 from USBiological Life Science
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CNO Antibody - abx034847 from Abbexa
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Cappuccino homolog antibody - H00055330-M02 from Acris Antibodies
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Cappuccino homolog antibody - H00055330-M02A from Acris Antibodies
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Rabbit Anti-Human CNO (Center) - 102-14807 from RayBiotech
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CNO antibody - 18217-1-AP from Proteintech Group
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CNO antibody (Center) - STJ48239 from St John's Laboratory Ltd
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CNO, Polyclonal Antibody - MBS2524589 from MyBioSource
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CNO Antibody - EPP11694 from Elabscience
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Anti-CNO (aa 114-143) polyclonal antibody - DPABH-13342 from Creative Diagnostics
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