| Gene Symbol |
BLOC1S4
|
| Entrez Gene |
55330
|
| Alt Symbol |
BCAS4L, BLOS4, CNO
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
|
| Other Description |
BLOC-1 subunit 4|biogenesis of lysosome-related organelles complex 1 subunit 4|cappuccino homolog|protein cappuccino homolog
|
| Swissprots |
Q6NVY6 Q96G84 Q9NUP1
|
| Accessions |
EAW82382 Q9NUP1 AF085849 AI679712 AK002092 BAA92080 BC001818 BC009890 BC067815 AAH67815 NM_018366 NP_060836
|
| Function |
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:17182842}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|