MYH10

Gene Symbol	MYH10
Entrez Gene	4628
Alt Symbol	NMMHC-IIB, NMMHCB
Species	Human
Gene Type	protein-coding
Description	myosin, heavy chain 10, non-muscle
Other Description	cellular myosin heavy chain, type B|myosin heavy chain, nonmuscle type B|myosin, heavy polypeptide 10, non-muscle|myosin-10|nonmuscle myosin II heavy chain-B|nonmuscle myosin heavy chain IIB
Swissprots	Q6PK16 P35580 Q4LE45 Q16087 Q149N4 Q149N3 F8VTL3 Q12989 Q9BWG0 B2RWP9 D3DTS1
Accessions	AAC50619 AAC50620 EAW90046 EAW90047 EAW90048 EAW90049 EAW90050 P35580 AB210026 BAE06108 AB621820 BAK64156 AF086505 AK026977 BC000280 AAH00280 BC008968 AAH08968 BC117690 AAI17691 BC117691 AAI17692 BC144668 AAI44669 BC150634 AAI50635 BE799557 BG421687 BG723653 BU173337 CA443268 DA737414 DQ925667 ABL59894 M69181 AAA99177 S67247 AAB28952 U15618 AAA87712 U34304 AAA84880 XM_005256651 XP_005256708 XM_011523875 XP_011522177 XM_011523876 XP_011522178 XM_011523877 XP_011522179 XM_011523878 XP_011522180 XM_011523879 XP_011522181 XM_011523880 XP_011522182 NM_001256012 NP_001242941 NM_001256095 NP_001243024 NM_005964 NP_005955
Function	Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:20603131}.
Subcellular Location	Cell projection, lamellipodium {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:22480440}. Note=Colocalizes with MCC at the leading edge of migrating cells.
Tissue Specificity	Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum. {ECO:0000269|PubMed:7782316}.
Top Pathways	Tight junction, Salmonella infection, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human MYH10 ELISA Kit (Sandwich ELISA) - LS-F6481 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Human MYH10 ELISA Kit - abx152418 from Abbexa Category ELISA Kit Sensitivity 0.057 ng/ml Range 0.156 ng/ml - 10 ng/ml

Myosin Heavy Chain 10, Non Muscle, MYH10, Human, ELISA Kit - E-EL-H0718 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Myosin Heavy Chain 10, Non Muscle (MYH10), Human, ELISA Kit - SED423Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.057ng/mL Range 0.156-10ng/mL

Myosin Heavy Chain 10, Non Muscle, MYH10, Rabbit, ELISA Kit - E-EL-RB2151 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Myosin Heavy Chain 10, Non Muscle, MYH10, Chicken, ELISA Kit - E-EL-Ch0574 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Myosin Heavy Chain 10, Non Muscle, MYH10, Porcine, ELISA Kit - E-EL-P1737 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Myosin Heavy Chain 10, Non Muscle, MYH10, Sheep, ELISA Kit - E-EL-S0206 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Myosin Heavy Chain 10, Non Muscle, MYH10, Monkey, ELISA Kit - E-EL-MK0544 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

myosin, heavy chain 10, non-muscle, ELISA Kit - MBS9316086 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MYH10(Myosin Heavy Chain 10, Non Muscle) ELISA Kit - E-EL-H0718 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human MYH10 (Myosin Heavy Chain 10, Non Muscle) CLIA Kit - E-CL-H0522 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

MYH10, ELISA Kit - MBS2506254 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

MYH10, ELISA Kit - MBS2512654 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL

MYH10, ELISA Kit - MBS2511198 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

MYH10, ELISA Kit - MBS2506905 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

MYH10, ELISA Kit - MBS2510309 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

MYH10, ELISA Kit - MBS2508785 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

ELISA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) - SED423Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) - SED423Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human MYH10(Myosin Heavy Chain 10, Non Muscle) ELISA Kit - E-EL-H0718 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mLng/mL Range 0.16~10 ng/mL

Human CALD (Caldesmon) CLIA Kit - E-CL-H0477 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Human MYH10 (Myosin Heavy Chain 10, Non Muscle) CLIA Kit - E-CL-H0522 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human MYH10 ELISA Kit (Sandwich ELISA) - LS-F20983 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.094 ng/ml Range 0.156-10 ng/ml

Myosin Heavy Chain 10, Non Muscle (MYH10), Human, ELISA Kit - DL-MYH10-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

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