MYH10

Gene Symbol MYH10
Entrez Gene 4628
Alt Symbol NMMHC-IIB, NMMHCB
Species Human
Gene Type protein-coding
Description myosin, heavy chain 10, non-muscle
Other Description cellular myosin heavy chain, type B|myosin heavy chain, nonmuscle type B|myosin, heavy polypeptide 10, non-muscle|myosin-10|nonmuscle myosin II heavy chain-B|nonmuscle myosin heavy chain IIB
Swissprots Q6PK16 P35580 Q4LE45 Q16087 Q149N4 Q149N3 F8VTL3 Q12989 Q9BWG0 B2RWP9 D3DTS1
Accessions AAC50619 AAC50620 EAW90046 EAW90047 EAW90048 EAW90049 EAW90050 P35580 AB210026 BAE06108 AB621820 BAK64156 AF086505 AK026977 BC000280 AAH00280 BC008968 AAH08968 BC117690 AAI17691 BC117691 AAI17692 BC144668 AAI44669 BC150634 AAI50635 BE799557 BG421687 BG723653 BU173337 CA443268 DA737414 DQ925667 ABL59894 M69181 AAA99177 S67247 AAB28952 U15618 AAA87712 U34304 AAA84880 XM_005256651 XP_005256708 XM_011523875 XP_011522177 XM_011523876 XP_011522178 XM_011523877 XP_011522179 XM_011523878 XP_011522180 XM_011523879 XP_011522181 XM_011523880 XP_011522182 NM_001256012 NP_001242941 NM_001256095 NP_001243024 NM_005964 NP_005955
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:20603131}.
Subcellular Location Cell projection, lamellipodium {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:22480440}. Note=Colocalizes with MCC at the leading edge of migrating cells.
Tissue Specificity Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum. {ECO:0000269|PubMed:7782316}.
Top Pathways Tight junction, Salmonella infection, Regulation of actin cytoskeleton

MYH10 Antibody Blocking Peptide - LS-E15556 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MYH10 Blocking Peptide - 33R-9945 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

MYH10 fusion protein - Ag16113 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

MYH10 fusion protein - Ag17069 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human MYH10, His-tagged - MYH10-29710TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Myosin Heavy Chain 10, Non Muscle (MYH10) - RPD423Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Myosin Heavy Chain 10, Non Muscle (MYH10) - RPD423Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Myosin-10(MYH10) - CSB-YP015290HU CSB-EP015290HU CSB-BP015290HU CSB-MP015290HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

non-muscle heavy chain 10 Myosin Protein - NBP2-38824PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

non-muscle heavy chain 10 Myosin Protein - NBP2-38566PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

MYH10 Peptide, Human - M34GP09985H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

MYH10 Recombinant Protein (OPCD05492) - OPCD05492 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human

Myosin-10 (MYH10), Recombinant Protein - MBS955851 from MyBioSource

Category Protein
Prices $1,715.00, $1,875.00, $2,030.00, $2,140.00, $2,340.00, $2,370.00, $2,675.00, $2,935.00, $3,385.00, $4,230.00
Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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