PPIH

Gene Symbol PPIH
Entrez Gene 10465
Alt Symbol CYP-20, CYPH, SnuCyp-20, USA-CYP
Species Human
Gene Type protein-coding
Description peptidylprolyl isomerase H (cyclophilin H)
Other Description PPIase h|U-snRNP-associated cyclophilin SnuCyp-20|U-snRNP-associated cyclophilin SunCyp-20|USA-CyP SnuCyp-20|cyclophilin H|peptidyl-prolyl cis-trans isomerase H|rotamase H|small nuclear ribonucleoprotein particle-specific cyclophilin H
Swissprots O43447 A6NNE7
Accessions EAX07151 EAX07152 EAX07153 EAX07154 EAX07155 EAX07156 O43447 AF016371 AAC51927 AF036331 AAC60793 AF086102 AK294288 BAH11725 AK309438 AK310052 AK311979 BAG34918 BC003412 AAH03412 BT019343 AAV38150 BU955702 CR541899 CAG46697 CR541920 CAG46718 DQ890971 ABM81897 DQ894146 ABM85072 HG491950 XM_005270362 XP_005270419 XM_005270366 XP_005270423 XM_011540508 XP_011538810 XR_426585 XR_946523 XR_946524 XR_946525 NM_006347 NP_006338
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone. {ECO:0000269|PubMed:11823439, ECO:0000269|PubMed:12875835, ECO:0000269|PubMed:9570313}.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:9570313}. Cytoplasm {ECO:0000269|PubMed:9570313}. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
Top Pathways Spliceosome

PPIH (C-1) - sc-377217 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PPIH (C-1): sc-377217. Western blot analysis of PPIH expression in non-transfected 293T: sc-117752 (A), mouse PPIH transfected 293T: sc-125851 (B) and HL-60 (C) whole cell lysates.

PPIH (C-5) - sc-390798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PPIH (C-5): sc-390798. Western blot analysis of PPIH expression in HL-60 (A) and Hep G2 (B) whole cell lysates.

PPIH (C-15) - sc-79697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PPIH (C-15): sc-79697. Western blot analysis of PPIH expression in non-transfected: sc-117752 (A) and human PPIH transfected: sc-110830 (B) 293T whole cell lysates.

PPIH (G-6) - sc-377420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PPIH (G-6): sc-377420. Western blot analysis of PPIH expression in non-transfected: sc-117752 (A) and mouse PPIH transfected: sc-125851 (B) 293T whole cell lysates.

PPIH (H-38) - sc-292646 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PPIH (H-38): sc-292646. Western blot analysis of PPIH expression in HL-60 (A), HeLa (B) and THP-1 (C) whole cell lysates.

PPIH (T-14) - sc-79700 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PPIH (T-14): sc-79700. Western blot analysis of PPIH expression in non-transfected: sc-117752 (A) and human PPIH transfected: sc-110830 (B) 293T whole cell lysates.

PPIH (N-13) - sc-79699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PPIH antibody - ab37397 from Abcam

Prices $359.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-PPIH antibody (ab37397) at 1/2000 dilution + E coli derived fusion protein at 0.25 µgSecondaryGoat anti IgY HRP at 1/1000 dilutiondeveloped using the ECL technique

Anti-PPIH / Cyclophilin H Antibody (clone 2D11) - LS-C338817 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPIH (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PPIH.

Anti-PPIH / Cyclophilin H Antibody (clone 1C6) - LS-C340629 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPIH (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PPIH.

Anti-PPIH / Cyclophilin H Antibody (aa35-84) - LS-C116453 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPIH antibody LS-C116453 Western blot of THP-1 cell lysate.

Anti-PPIH / Cyclophilin H Antibody (aa71-120) - LS-C116454 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPIH antibody LS-C116454 Western blot of HepG2 cell lysate.

PPIH Antibody - NBP2-32416 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PPIH Antibody [NBP2-32416] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp

PPIH Antibody - NBP2-19899 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PPIH Antibody [NBP2-19899] - Sample (30 ug of whole cell lysate) A: HeLa 12% SDS PAGE gel, diluted at 1:1000.

PPIH Antibody - NBP1-57630 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PPIH Antibody - NBP1-55448 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PPIH Antibody [NBP1-55448] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

PPIH Antibody - NB100-75346 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: PPIH Antibody [NB100-75346] - E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-PPIH )

PPIH Antibody - H00010465-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-PPIH antibody produced in rabbit - SAB2702100 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPIH: <B>Cat. No. SAB2702100</B>: Immunohistochemical analysis of paraffin-embedded Mahlarvu xenograft using PPIH antibody at a 1:500 dilution.

Anti-PPIH antibody produced in chicken - GW21963F from Sigma-Aldrich

Prices $267.50
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-PPIH antibody produced in rabbit - SAB2105815 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPIH: <B>Cat. No. SAB2105815</B>: PPIH in HepG2 cell lysates with PPIH antibody at 1.0 μg/mL.

Anti-PPIH antibody produced in rabbit - HPA059019 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPIH: <B>Cat. No. HPA059019</B>: Immunohistochemical staining of Human colon shows strong cytoplasmic positivity in glandular cells.

Anti-PPIH, (N-terminal) antibody produced in rabbit - SAB2105814 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPIH (N-Terminal): <B>Cat. No. SAB2105814</B>: PPIH in THP-1 cell lysates with PPIH antibody at 1.0 μg/mL.

PPIH antibody - N-terminal region (ARP52153_P050) - ARP52153_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPIH antibody - middle region (ARP52154_P050) - ARP52154_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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