PDE7A

Gene Symbol PDE7A
Entrez Gene 5150
Alt Symbol HCP1, PDE7
Species Human
Gene Type protein-coding
Description phosphodiesterase 7A
Other Description TM22|high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A|phosphodiesterase isozyme 7
Swissprots A0AVH6 A8K9G5 Q13946 A8K436 O15380 Q96T72
Accessions CAD29836 CAV30707 CBX54286 CBX54287 CDL93463 CDL96991 EAW86883 EAW86884 EAW86885 EAW86886 Q13946 AF332652 AAK57640 AI632383 AK057586 AK290801 BAF83490 AK292680 BAF85369 AW387924 AY266364 AAP31236 BC058025 BC126360 AAI26361 BM818331 CN414361 DB146108 DB460103 DR000686 HG501292 HQ258418 ADR83172 N49050 U67932 AAB65772 XM_011517540 XP_011515842 NM_001242318 NP_001229247 NM_002603 NP_002594 NM_002604
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. {ECO:0000269|PubMed:19350606}.
Subcellular Location Isoform PDE7A1: Cytoplasm, cytosol. Note=PDE7A1 (57 kDa) is located mostly to soluble cellular fractions.
Tissue Specificity PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
Top Pathways Morphine addiction, Purine metabolism

PDE7A (B-11) - sc-398031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE7A (B-11): sc-398031. Western blot analysis of PDE7A expression in HuT 78 whole cell lysate.

PDE7A (C-21) - sc-11131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE7A (C-21): sc-11131. Western blot analysis of PDE7A expression in HuT 78 whole cell lysate.

PDE7A1/2 (H-52) - sc-25566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PDE7A1/2 (H-52): sc-25566. Western blot analysis of PDE7A1/2 expressin in HuT 78 whole cell lysate.

PDE7A1/2 (H-7) - sc-28374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE7A1/2 (H-7): sc-28374. Western blot analysis of PDE7A1/2 expression in HuT 78 whole cell lysate.

PDE7A1/3 (F-5) - sc-271324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE7A1/3 (F-5): sc-271324. Western blot analysis of PDE7A1/3 expression in L8 (A) and Hut 78 (B) whole cell lysates.

PDE7A1/3 (H-50) - sc-25567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PDE7A1/3 (F-8) - sc-166550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE7A1/3 (F-8): sc-166550. Western blot analysis of PDE7A1/3 expression in HuT 78 whole cell lysate.

PDE7A1/3 (N-19) - sc-11128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PDE7A antibody - ab14616 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PDE7A antibody (ab14616) at 1/500 dilutionLane 1 : Rat LungsLane 2 : Rat KidneyLane 3 : Rat TestisLane 4 : Rat PC-PDE7ALane 5 : Rat HeartLane 6 : Rat BrainLane 7 : Rat Heart

Anti-PDE7A antibody - ab130601 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PDE7A antibody (ab130601) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

Anti-PDE7A antibody [EPR7731] - ab154857 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7731
Anti-PDE7A antibody [EPR7731] (ab154857) at 1/1000 dilution + HuT78 cell lysate at 10 µgSecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PDE7A antibody - C-terminal - ab136298 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PDE7A antibody - C-terminal (ab136298) at 1 µg/ml + 721_B cell lysate at 10 µg

Anti-PDE7A Antibody (C-Terminus) - LS-C82356 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody - LS-C90185 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, AP) - LS-C265911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, FITC) - LS-C265913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, APC) - LS-C265912 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, Biotin) - LS-C265914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, Azide-free, HRP) - LS-C265915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa65-94, PE) - LS-C265916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (C-Terminus) - LS-C151712 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDE7A antibody Western Blot of Placenta.

Anti-PDE7A Antibody (aa65-94) - LS-C323894 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa338-387) - LS-C169752 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE7A Antibody (aa66-94) - LS-C163473 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PDE7A Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The PDE7A antibody detected the PDE7A protein (arrow).

Anti-PDE7A Antibody (N-Terminus) IHC-plus™ - LS-A703 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PDE7A antibody LS-A703 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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