PDE7A

Gene Symbol PDE7A
Entrez Gene 5150
Alt Symbol HCP1, PDE7
Species Human
Gene Type protein-coding
Description phosphodiesterase 7A
Other Description TM22|high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A|phosphodiesterase isozyme 7
Swissprots A0AVH6 A8K9G5 Q13946 A8K436 O15380 Q96T72
Accessions CAD29836 CAV30707 CBX54286 CBX54287 CDL93463 CDL96991 EAW86883 EAW86884 EAW86885 EAW86886 Q13946 AF332652 AAK57640 AI632383 AK057586 AK290801 BAF83490 AK292680 BAF85369 AW387924 AY266364 AAP31236 BC058025 BC126360 AAI26361 BM818331 CN414361 DB146108 DB460103 DR000686 HG501292 HQ258418 ADR83172 N49050 U67932 AAB65772 XM_011517540 XP_011515842 NM_001242318 NP_001229247 NM_002603 NP_002594 NM_002604
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. {ECO:0000269|PubMed:19350606}.
Subcellular Location Isoform PDE7A1: Cytoplasm, cytosol. Note=PDE7A1 (57 kDa) is located mostly to soluble cellular fractions.
Tissue Specificity PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
Top Pathways Morphine addiction, Purine metabolism

Active human PDE7A protein fragment - ab125786 from Abcam

Category Protein
Prices $302.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of ab125786.

Active human PDE7A protein fragment - ab79740 from Abcam

Category Protein
Prices $302.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Human
10% SDS-PAGE showing ab79740 at approximately 66kDa (1µg).

Active mouse PDE7A protein fragment - ab198756 from Abcam

Category Protein
Prices $1,250.00
Sizes 10 µg
Source Baculovirus infected sf9 cells
Species Mouse
Activity assay using ab198756.

Active rat PDE7A protein fragment - ab198419 from Abcam

Category Protein
Prices $1,250.00
Sizes 10 µg
Source Baculovirus infected sf9 cells
Species Rat
Activity assay using ab198419.

Human PDE7A full length protein - ab152598 from Abcam

Category Protein
Source Wheat germ
Species Human
ab152598 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human PDE7A protein fragment - ab152599 from Abcam

Category Protein
Source Wheat germ
Species Human
ab152599 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PDE7A Antibody Blocking Peptide - LS-E4738 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PDE7A Antibody Blocking Peptide - LS-E23488 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PDE7A Antibody Blocking Peptide - LS-E23487 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PDE7A Antibody Blocking Peptide - LS-E29215 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human PDE7A Protein - H00005150-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human PDE7A Protein - H00005150-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

PDE7A-Antibody-N-term-Blocking-Peptide - BP17110a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PDE7A - H00005150-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

PDE7A - H00005150-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PDE7A - H00005150-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PDE7A Control Peptide - AP10247CP-N from Acris Antibodies

Category Peptide
Prices $255.00
Sizes 100 µg

PDE7A fusion protein - Ag16253 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PDE7A fusion protein - Ag24474 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET30a
Species Human

PDE7A fusion protein - ag17717 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

PDE7A, Active Human Recombinant Protein - GWB-2500BE from Genway Biotech

Category Protein
Prices $600.00
Sizes 10 µg
Species Human
PDE7A, Active Human Recombinant Protein

Recombinant Human Phosphodiesterase 7A, GST-tagged, Active - PDE7A-481H from Creative Biomart

Category Protein
Source Sf9 insect cells using baculovirus.

Recombinant Human PDE7A, GST-tagged - PDE7A-1606H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human PDE7A - PDE7A-332H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Human PDE7A (Active), GST-tagged - PDE7A-1531H from Creative Biomart

Category Protein
Source Sf9 Cells
Species Human
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