KPNA3

Gene Symbol	KPNA3
Entrez Gene	3839
Alt Symbol	IPOA4, SRP1, SRP1gamma, SRP4, hSRP1
Species	Human
Gene Type	protein-coding
Description	karyopherin alpha 3 (importin alpha 4)
Other Description	SRP1-gamma|importin alpha 4|importin alpha Q2|importin alpha-3|importin subunit alpha-3|importin subunit alpha-4|importin-alpha-Q2|karyopherin subunit alpha-3|qip2
Swissprots	O00191 O00505 Q96AA7 Q5JVM9 O43195
Accessions	EAX08837 EAX08838 EAX08839 O00505 AF005263 AAQ13404 AF034756 AAB87693 AI309735 AK223480 BAD97200 AK290528 BAF83217 AK291000 BAF83689 AU132188 BC017355 AAH17355 BC024202 AAH24202 BC035090 AAH35090 D89618 BAA20378 DN991804 DQ892644 ABM83570 DQ895882 ABM86808 Y12394 CAA73026 NM_002267 NP_002258
Function	Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non- classical NLS. Recognizes NLSs of influenza A virus nucleoprotein probably thro
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity	Ubiquitous. Highest levels in heart and skeletal muscle.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KPNA3 peptide - ab23142 from Abcam Category Peptide Species Human

Human KPNA3 protein fragment - ab114747 from Abcam Category Protein Source Wheat germ Species Human

KPNA3 / Importin Alpha 4 Antibody Blocking Peptide - LS-E19700 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KPNA3 / Importin Alpha 4 Antibody Blocking Peptide - LS-E25665 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KPNA3 / Importin Alpha 4 Antibody Blocking Peptide - LS-E31004 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KPNA3 Partial Recombinant Protein - H00003839-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

KPNA3 Blocking Peptide - NBP1-76299PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

KPNA3-Antibody-C-term-Blocking-Peptide - BP6767b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KPNA3-Antibody-N-term-Blocking-Peptide - BP6767a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KPNA3 blocking peptide - GTX26038-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

KPNA2 protein (His tag) - 80R-2131 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

KPNA3 Peptide - AC21-0495-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

KPNA3 / Importin alpha-3 - H00003839-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KPNA3 / Importin alpha-3 - H00003839-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KPNA3 / Importin alpha-3 control peptide - AP26276CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

KPNA3 Peptide - 45-813P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

KPNA3 Peptide - 5985P from ProSci Category Peptide Species Human

KPNA3 fusion protein - ag2122 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human KPNA3 - KPNA3-29810TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Importin subunit alpha-3(KPNA3) - CSB-YP012485HU CSB-EP012485HU CSB-BP012485HU CSB-MP012485HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KPNA3 Protein - abx163201 from Abbexa Category Protein Species Human

Recombinant Karyopherin Alpha 3 (KPNa3) - RPC556Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Karyopherin Alpha 3 (KPNa3) - RPC556Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

KPNA3 / Importin alpha-3 - TP307314 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

KPNA3/IPOA4, Peptide - MBS425381 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

Search more