Gene Symbol | RMI2 |
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Entrez Gene | 116028 |
Alt Symbol | BLAP18, C16orf75 |
Species | Human |
Gene Type | protein-coding |
Description | RecQ mediated genome instability 2 |
Other Description | BLM-associated protein of 18 kDa|RMI2, RecQ mediated genome instability 2, homolog|recQ-mediated genome instability protein 2 |
Swissprots | Q8TBL0 B3KVZ6 Q49AE2 Q96E14 |
Accessions | EAW85155 Q96E14 AK123764 BAG53958 BC013040 AAH13040 BC022427 AAH22427 BC031016 AAH31016 BC039361 AAH39361 CN311350 NM_152308 NP_689521 NR_130754 |
Function | Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM. {ECO:0000269|PubMed:18923082, ECO:0000269|PubMed:18923083}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18923082}. Note=Colocalizes with BLM at nuclear DNA repair foci. |
Top Pathways | Fanconi anemia pathway |
RMI2 (A-14) - sc-167291 from Santa Cruz Biotechnology
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RMI2 (C-16) - sc-167292 from Santa Cruz Biotechnology
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RMI2 (E-12) - sc-167293 from Santa Cruz Biotechnology
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Anti-RMI2 antibody - ab108491 from Abcam
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Anti-RMI2 antibody - ab122685 from Abcam
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RMI2 Antibody - NBP1-89962 from Novus Biologicals
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Anti-RMI2 antibody produced in rabbit - HPA040995 from Sigma-Aldrich
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Anti-RMI2 (aa 99-146) polyclonal antibody - DPABH-20992 from Creative Diagnostics
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Anti-RMI2 polyclonal antibody - DPABH-25475 from Creative Diagnostics
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Anti-RMI2 monoclonal antibody - DCABH-201366 from Creative Diagnostics
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Anti-RMI2 antibody - STJ110821 from St John's Laboratory Ltd
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RMI2 - A8523 from NeoScientific
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RMI2 Polyclonal Antibody - A8523 from ABclonal
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RMI2, Polyclonal Antibody - MBS9128171 from MyBioSource
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RMI2 Antibody - abx005864 from Abbexa
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RMI2 polyclonal antibody - BS71274 from Bioworld Technology
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RMI2 Polyclonal Antibody - EAP3648 from Elabscience
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Rabbit anti-RMI2 Antibody - 144-08523-50 from RayBiotech
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Anti-RMI2 Antibody - CQA3500 from Cohesion Biosciences
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RMI2 Polyclonal Antibody - A8523 from ARP American Research Products
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Anti-RMI2 / C16orf75 Antibody - LS-C410058 from LifeSpan Bioscience
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RMI2, Polyclonal Antibody - MBS2541087 from MyBioSource
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