RMI2

Gene Symbol	RMI2
Entrez Gene	116028
Alt Symbol	BLAP18, C16orf75
Species	Human
Gene Type	protein-coding
Description	RecQ mediated genome instability 2
Other Description	BLM-associated protein of 18 kDa|RMI2, RecQ mediated genome instability 2, homolog|recQ-mediated genome instability protein 2
Swissprots	Q8TBL0 B3KVZ6 Q49AE2 Q96E14
Accessions	EAW85155 Q96E14 AK123764 BAG53958 BC013040 AAH13040 BC022427 AAH22427 BC031016 AAH31016 BC039361 AAH39361 CN311350 NM_152308 NP_689521 NR_130754
Function	Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM. {ECO:0000269|PubMed:18923082, ECO:0000269|PubMed:18923083}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:18923082}. Note=Colocalizes with BLM at nuclear DNA repair foci.
Top Pathways	Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RMI2 CRISPR/Cas9 KO Plasmid (h) - sc-407104 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 HDR Plasmid (h) - sc-407104-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 Double Nickase Plasmid (h) - sc-407104-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 Double Nickase Plasmid (h2) - sc-407104-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 CRISPR Activation Plasmid (h) - sc-407104-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 CRISPR Activation Plasmid (h2) - sc-407104-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 Lentiviral Activation Particles (h) - sc-407104-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 Lentiviral Activation Particles (h2) - sc-407104-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 siRNA (h) - sc-93410 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RMI2 shRNA Plasmid (h) - sc-93410-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RMI2 shRNA (h) Lentiviral Particles - sc-93410-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RMI2 RNAi - H00116028-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU129651 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4426 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4426 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

RMI2 siRNA (Human) - CRJ4478 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RMI2 - MBS8201697 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RMI2 CRISPR/Cas9 KO Plasmid (h2) - sc-407104-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RMI2 HDR Plasmid (h2) - sc-407104-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human RMI2 (NM_152308.1) - SHH396184 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human C16orf75(NM_152308.1) - SHG116531 from Creative biogene Category siRNA Species Reactivities Human

Human RMI2 siRNA - orb274979 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RMI2 shRNA Plasmid (Human) - CHJ4478 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RMI2 miRNA 3'UTR clone - MiUTR1H-01157 from Creative biogene Species Reactivities Human

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