| Gene Symbol |
ARPC4
|
| Entrez Gene |
10093
|
| Alt Symbol |
ARC20, P20-ARC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
actin related protein 2/3 complex, subunit 4, 20kDa
|
| Other Description |
actin-related protein 2/3 complex subunit 4|arp2/3 complex 20 kDa subunit|arp2/3 protein complex subunit p20
|
| Swissprots |
Q6P0W5 F6TTL5 E7ETI0 C9JWM7 O15509 P59998 Q96QJ3
|
| Accessions |
EAW63998 EAW64001 P59998 AF006087 AAB64192 AF019888 AAB71548 AI612891 AK074205 AW408422 BC012596 AAH12596 BC065423 BC152790 AAI52791 BG938423 BI768875 BI910730 BM045872 BQ688329 BX419672 DA226584 DA909066 DB060690 NM_001024959 NP_001020130 NM_001024960 NP_001020131 NM_001198780 NP_001185709 NM_005718 NP_005709
|
| Function |
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9359840}. Cell projection {ECO:0000269|PubMed:9359840}.
|
| Top Pathways |
Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton
|