ARPC4

Gene Symbol ARPC4
Entrez Gene 10093
Alt Symbol ARC20, P20-ARC
Species Human
Gene Type protein-coding
Description actin related protein 2/3 complex, subunit 4, 20kDa
Other Description actin-related protein 2/3 complex subunit 4|arp2/3 complex 20 kDa subunit|arp2/3 protein complex subunit p20
Swissprots Q6P0W5 F6TTL5 E7ETI0 C9JWM7 O15509 P59998 Q96QJ3
Accessions EAW63998 EAW64001 P59998 AF006087 AAB64192 AF019888 AAB71548 AI612891 AK074205 AW408422 BC012596 AAH12596 BC065423 BC152790 AAI52791 BG938423 BI768875 BI910730 BM045872 BQ688329 BX419672 DA226584 DA909066 DB060690 NM_001024959 NP_001020130 NM_001024960 NP_001020131 NM_001198780 NP_001185709 NM_005718 NP_005709
Function Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9359840}. Cell projection {ECO:0000269|PubMed:9359840}.
Top Pathways Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton

Human ARPC4 ORF Clone(NM_001024959.2) - CDCR342335 from Creative Biomart

Species Human
Accession NM_001024959.2

Human ARPC4 ORF Clone(NM_001024959.2) - CDCR342336 from Creative Biomart

Species Human
Accession NM_001024959.2

Human ARPC4 ORF Clone(NM_001024960.2) - CDCR342337 from Creative Biomart

Species Human
Accession NM_001024960.2

Human ARPC4 ORF Clone(NM_001024960.2) - CDCR342338 from Creative Biomart

Species Human
Accession NM_001024960.2

Human ARPC4 ORF Clone(NM_001198780.1) - CDCR358964 from Creative Biomart

Species Human
Accession NM_001198780.1

Human ARPC4 ORF Clone(NM_001198780.1) - CDCR358965 from Creative Biomart

Species Human
Accession NM_001198780.1
The plasmid was transfected into 293H adherent cells with Sinofection reagent (Cat# STF01). After 48 h, Immunofluorescence staining of cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Flag Tag monoclonal antibody (CST#8146S) at 37℃ 1 hour. Then cells were stained with Goat Anti-mouse IgG secondary antibody. The fluorescent signal is detected by fluorescence microscope. Each expression experiment has negative control.

Human ARPC4 ORF Clone(NM_001024959.2) - CDCR342335 from Creative biogene

Species Human

Human ARPC4 ORF Clone(NM_001024960.2) - CDCR342337 from Creative biogene

Species Human

Human ARPC4 ORF clone (NM_001198780.1) - CDCR030386 from Creative biogene

Species Human
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