Gene Symbol | FBN1 |
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Entrez Gene | 2200 |
Alt Symbol | ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 |
Species | Human |
Gene Type | protein-coding |
Description | fibrillin 1 |
Other Description | fibrillin 15|fibrillin-1 |
Swissprots | D2JYH6 B2RUU0 P35555 Q15972 Q75N87 |
Accessions | AAB25244 ACZ58372 BAD16737 BAD16738 BAD16739 CCQ42969 CCQ42970 EAW77353 EAW77354 P35555 AB208840 BAD92077 AK304737 BAG65498 AK309616 BC094721 BC146854 AAI46855 L13923 AAB02036 W81203 X62008 CAB56534 X63556 CAA45118 NM_000138 NP_000129 |
Function | Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. {ECO:0000269|PubMed:15062093}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:21989719}. |
fibrillin-1 (H-109) - sc-20084 from Santa Cruz Biotechnology
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fibrillin-1 (N-19) - sc-7541 from Santa Cruz Biotechnology
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fibrillin-1 (C-19) - sc-7540 from Santa Cruz Biotechnology
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fibrillin-1 (2Q629) - sc-71108 from Santa Cruz Biotechnology
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Anti-Fibrillin 1 antibody - ab53076 from Abcam
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Anti-Fibrillin 1 antibody [3H6] - ab124334 from Abcam
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Anti-FBN1 / Fibrillin 1 Antibody - LS-C23544 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2093-2871) - LS-C23550 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody - LS-C23553 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody - LS-C23555 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (clone 11C1.3) - LS-C83401 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2737-2750) - LS-C108910 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (clone 11C1.3) - LS-C87966 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (clone 11C1.3, Azide-free) - LS-C87967 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2772-2872, AP) - LS-C219284 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2772-2872, PE) - LS-C219287 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2772-2872, Azide-free, HRP) - LS-C219286 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2772-2872, APC) - LS-C219285 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa2811-2860) - LS-C118450 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa246-389, Biotin) - LS-C297307 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa81-236, Biotin) - LS-C297519 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (Asn2843) - LS-C176024 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa81-236) - LS-C293867 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa246-389, FITC) - LS-C303099 from LifeSpan Bioscience
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Anti-FBN1 / Fibrillin 1 Antibody (aa246-389) - LS-C293874 from LifeSpan Bioscience
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