Gene Symbol | FBN1 |
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Entrez Gene | 2200 |
Alt Symbol | ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 |
Species | Human |
Gene Type | protein-coding |
Description | fibrillin 1 |
Other Description | fibrillin 15|fibrillin-1 |
Swissprots | D2JYH6 B2RUU0 P35555 Q15972 Q75N87 |
Accessions | AAB25244 ACZ58372 BAD16737 BAD16738 BAD16739 CCQ42969 CCQ42970 EAW77353 EAW77354 P35555 AB208840 BAD92077 AK304737 BAG65498 AK309616 BC094721 BC146854 AAI46855 L13923 AAB02036 W81203 X62008 CAB56534 X63556 CAA45118 NM_000138 NP_000129 |
Function | Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. {ECO:0000269|PubMed:15062093}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:21989719}. |
Human Fibrillin 1 protein fragment - ab114345 from Abcam
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FBN1 / Fibrillin 1 Antibody Blocking Peptide - LS-E27197 from LifeSpan Bioscience
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FBN1 / Fibrillin 1 Antibody Blocking Peptide - LS-E13614 from LifeSpan Bioscience
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Recombinant Human Fibrillin 1 Protein - H00002200-Q01 from Novus Biologicals
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Fibrillin 1 blocking peptide - GTX88271-PEP from GeneTex
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FBN1 peptide - orb72679 from Biorbyt
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FBN1 Blocking Peptide - 33R-6380 from Fitzgerald
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OTC protein (His tag) - 80R-2216 from Fitzgerald
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Human Fibrillin 1 Protein - abx066564 from Abbexa
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Human Fibrillin 1 Protein - abx066558 from Abbexa
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Human Fibrillin 1 Protein - abx066561 from Abbexa
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Human Fibrillin 1 Protein - abx066562 from Abbexa
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Human Fibrillin 1 Protein - abx066563 from Abbexa
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Fibrillin 1 Peptide - AC21-2017-P from Abcore
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Fibrillin-1 - H00002200-Q01-10 from Acris Antibodies
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Fibrillin-1 - H00002200-Q01-25 from Acris Antibodies
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Fibrillin 1 (FBN1), Human - 20-6865 from ARP American Research Products
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Fibrillin 1 (FBN1), Human - 20-6866 from ARP American Research Products
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Fibrillin 1 (FBN1), Human - 20-6867 from ARP American Research Products
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Fibrillin 1 (FBN1), Human - 20-6868 from ARP American Research Products
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Fibrillin 1 (FBN1), Human - 20-6869 from ARP American Research Products
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FBN1 Peptide - 42-241P from ProSci
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Recombinant Human FBN1 - FBN1-28892TH from Creative Biomart
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Recombinant Fibrillin 1 (FBN1) - RPA593Hu01 from Uscn Life Science Inc.
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Recombinant Fibrillin 1 (FBN1) - RPA593Hu02 from Uscn Life Science Inc.
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