PTPRQ

Gene Symbol	PTPRQ
Entrez Gene	374462
Alt Symbol	DFNB84, DFNB84A, PTPGMC1, R-PTP-Q
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, Q
Other Description	phosphatidylinositol phosphatase PTPRQ|phosphotidylinositol phosphatase PTPRQ|protein-tyrosine phosphatase, receptor-type, expressed by glomerular mesangial cells
Swissprots	Q9UMZ3
Accessions	Q9UMZ3 AF169351 AAD50277 BM750287 DA545412 DB305536 DB318211 DB341961 DN831929 DV080144 DV080238 DV080465 DV080607 DV080649 DV080650 DV080661 DW009832 DW009898 DW009906 DY655367 EG327664 XM_011538290 XP_011536592 NM_001145026 NP_001138498
Function	Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal region of hair bundles. Can dephosphorylate a broad range of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and most phosphatidylinositol monophosphates and diphosphates. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by suppressing the phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCs and preadipocyte cells. {ECO:0000269|PubMed:19351528}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12837292}; Single-pass type I membrane protein {ECO:0000269|PubMed:12837292}.
Tissue Specificity	In developing kidney, it localizes to the basal membrane of podocytes, beginning when podocyte progenitors can first be identified in the embryonic kidney (at protein level). Expressed in lung and kidney. {ECO:0000269|PubMed:12837292, ECO:0000269|PubMed:20346435}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTPRQ ELISA Kit (Competitive EIA) - LS-F12450 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.78-50 ng/ml

ELISA Kit for Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) - SED603Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) - SED603Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse PTPRQ ELISA Kit (Custom ELISA) - LS-F15717 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.78-50 ng/ml

Rat PTPRQ ELISA Kit (Custom ELISA) - LS-F15716 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.78-50 ng/ml

Human Phosphotidylinositol phosphatase PTPRQ ELISA Kit - abx250417 from Abbexa Category ELISA Kit Range 0.78 ng/ml - 50 ng/ml

Human PTPRQ ELISA Kit (Sandwich ELISA) - LS-F25425 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.78-50 ng/ml

Human Phosphotidylinositol phosphatase PTPRQ ELISA Kit - EKE52702 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.23 ng/mL Range 0.78-50 ng/mL

PTPRQ ELISA Kit (Human) : 96 Wells (OKEH02080) - OKEH02080 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.23 ng/mL Range 0.78 - 50 ng/mL

Human Phosphotidylinositol phosphatase PTPRQ ELISA Kit - EK2611 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.23ng/mL Range 0.78-50 ng/mL

Human Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit - AE25047HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.058 ng/mL Range 0.156-10 ng/mL

Phosphotidylinositol phosphatase PTPRQ, ELISA Kit - MBS9426449 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.23ng/mL Range 0.78-50 ng/mL

Phosphotidylinositol phosphatase PTPRQ, ELISA Kit - MBS2887478 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78-50 ng/mL

Phosphotidylinositol phosphatase PTPRQ, ELISA Kit - MBS762333 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/ml Range 0.78-50ng/ml

Human PTPRQ ELISA Kit (Competitive EIA) - LS-F39387 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.469 Range 0.78-50 ng/ml

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