PTPRQ

Gene Symbol PTPRQ
Entrez Gene 374462
Alt Symbol DFNB84, DFNB84A, PTPGMC1, R-PTP-Q
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, Q
Other Description phosphatidylinositol phosphatase PTPRQ|phosphotidylinositol phosphatase PTPRQ|protein-tyrosine phosphatase, receptor-type, expressed by glomerular mesangial cells
Swissprots Q9UMZ3
Accessions Q9UMZ3 AF169351 AAD50277 BM750287 DA545412 DB305536 DB318211 DB341961 DN831929 DV080144 DV080238 DV080465 DV080607 DV080649 DV080650 DV080661 DW009832 DW009898 DW009906 DY655367 EG327664 XM_011538290 XP_011536592 NM_001145026 NP_001138498
Function Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal region of hair bundles. Can dephosphorylate a broad range of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and most phosphatidylinositol monophosphates and diphosphates. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by suppressing the phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCs and preadipocyte cells. {ECO:0000269|PubMed:19351528}.
Subcellular Location Membrane {ECO:0000269|PubMed:12837292}; Single-pass type I membrane protein {ECO:0000269|PubMed:12837292}.
Tissue Specificity In developing kidney, it localizes to the basal membrane of podocytes, beginning when podocyte progenitors can first be identified in the embryonic kidney (at protein level). Expressed in lung and kidney. {ECO:0000269|PubMed:12837292, ECO:0000269|PubMed:20346435}.

Recombinant Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) - RPD603Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) - RPD603Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Phosphotidylinositol phosphatase PTPRQ(PTPRQ) ,partial - CSB-YP891561HU CSB-EP891561HU CSB-BP891561HU CSB-MP891561HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Phosphotidylinositol phosphatase PTPRQ (PTPRQ), partial, Recombinant Protein - MBS1345125 from MyBioSource

Category Protein
Prices $835.00, $835.00, $1,055.00, $1,055.00, $1,170.00, $1,170.00, $1,620.00, $1,620.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PTPRQ Recombinant Protein (OPCD06530) - OPCD06530 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human
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