| Gene Symbol |
HMGCS1
|
| Entrez Gene |
3157
|
| Alt Symbol |
HMGCS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
| Other Description |
3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)|hydroxymethylglutaryl-CoA synthase, cytoplasmic
|
| Swissprots |
B2RDL8 Q01581
|
| Accessions |
EAW56054 EAW56055 EAW56056 Q01581 AK095492 BAC04559 AK315593 BAG37965 AL050004 BC000297 AAH00297 BC082234 BC083514 AAH83514 BT007302 AAP35966 DB074885 DB078662 L25798 AAA62411 M15802 X66435 CAA47061 XM_011514034 XP_011512336 XM_011514035 XP_011512337 XM_011514036 XP_011512338 NM_001098272 NP_001091742 NM_002130 NP_002121
|
| Function |
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Terpenoid backbone biosynthesis, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism
|