HMGCS1

Gene Symbol HMGCS1
Entrez Gene 3157
Alt Symbol HMGCS
Species Human
Gene Type protein-coding
Description 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Other Description 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)|hydroxymethylglutaryl-CoA synthase, cytoplasmic
Swissprots B2RDL8 Q01581
Accessions EAW56054 EAW56055 EAW56056 Q01581 AK095492 BAC04559 AK315593 BAG37965 AL050004 BC000297 AAH00297 BC082234 BC083514 AAH83514 BT007302 AAP35966 DB074885 DB078662 L25798 AAA62411 M15802 X66435 CAA47061 XM_011514034 XP_011512336 XM_011514035 XP_011512337 XM_011514036 XP_011512338 NM_001098272 NP_001091742 NM_002130 NP_002121
Function This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Subcellular Location Cytoplasm.
Top Pathways Terpenoid backbone biosynthesis, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

cHMGCS (H-9) - sc-373681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cHMGCS (H-9): sc-373681. Western blot analysis of cHMGCS expression in non-transfected: sc-117752 (A) and mouse cHMGCS transfected: sc-119234 (B) 293T whole cell lysates.

cHMGCS (C-8) - sc-271543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cHMGCS (C-8): sc-271543. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic and nuclear staining of glandular cells.

cHMGCS (A-6) - sc-166763 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cHMGCS (A-6): sc-166763. Western blot analysis of cHMGCS expression in non-transfected: sc-117752 (A) and mouse cHMGCS transfected: sc-119231 (B) 293T whole cell lysates.

cHMGCS (H-70) - sc-33829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cHMGCS (H-70): sc-33829. Western blot analysis of cHMGCS expression in non-transfected: sc-117752 (A) and human cHMGCS transfected: sc-117385 (B) 293T whole cell lysates.

cHMGCS (C-20) - sc-32423 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cHMGCS (C-20): sc-32423. Western blot analysis of cHMGCS expression in Hep G2 whole cell lysate.

cHMGCS (D-20) - sc-32422 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cHMGCS (D-20): sc-32422. Western blot analysis of cHMGCS expression in Hep G2 whole cell lysate (A) and rat liver tissue extract (B).

Anti-HMGCS1 antibody - ab67242 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-HMGCS1 antibody (ab67242) at 1/500 dilution + human liver tissue lysate at 25 µg/mlSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody - LS-C308268 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody (aa293-467) - LS-C294547 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant HMG-CoA Synthase / HMGCS1.

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody (aa251-300) IHC-plus™ - LS-B4016 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HMGCS1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4016 concentration 5 ug/ml.

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody (aa442-470) - LS-C98391 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HMGCS1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody (aa290-317) - LS-C98392 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HMGCS1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-HMGCS1 / HMG-CoA Synthase 1 Antibody (C-Terminus) IHC-plus™ - LS-B11977 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

HMGCS1 Antibody - NBP2-16861 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HMGCS1 Antibody [NBP2-16861] - Sample (50 ug of whole cell lysate) A: Mouse Liver, 7. 5% SDS PAGE gel, diluted at 1:1000.

HMGCS1 Antibody - NBP1-54623 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HMGCS1 Antibody - NBP2-14094 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HMGCS1 Antibody - NBP2-36554 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HMGCS1 Antibody [NBP2-36554] - Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-HMGCS1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

HMGCS1 Antibody - H00003157-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HMGCS1 Antibody [H00003157-B01P] - Analysis of HMGCS1 expression in human liver.

HMGCS1 Antibody - H00003157-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-HMGCS1 antibody produced in rabbit - HPA036914 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HMGCS1: <B>Cat. No. HPA036914</B>: Immunohistochemical staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Anti-HMGCS1 antibody produced in mouse - SAB1400127 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-HMGCS1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400127</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~57.3 kDa using human liver lysate.

Anti-HMGCS1 antibody produced in rabbit - SAB2103201 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HMGCS1: <B>Cat. No. SAB2103201</B>: Immunohistochemistry of HMGCS1 in Human Skeletal Muscle tissue with HMGCS1 antibody at 5.0 μg/mL.

Anti-HMGCS1 antibody produced in rabbit - HPA036913 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HMGCS1:<B>Cat. No. HPA036913</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity with a granular pattern in glandular cells.

HMGCS1 antibody - middle region (ARP48564_P050) - ARP48564_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HMGCS1-Antibody-Center - AP6652c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
HMGCS1 Antibody (Center) (Cat.# AP6652c) western blot analysis in U87-MG cell line,mouse liver and rat liver lysates (35ug/lane).This demonstrates the HMGCS1 antibody detected the HMGCS1 protein (arrow).
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