HMGCS1

Gene Symbol HMGCS1
Entrez Gene 3157
Alt Symbol HMGCS
Species Human
Gene Type protein-coding
Description 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Other Description 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)|hydroxymethylglutaryl-CoA synthase, cytoplasmic
Swissprots B2RDL8 Q01581
Accessions EAW56054 EAW56055 EAW56056 Q01581 AK095492 BAC04559 AK315593 BAG37965 AL050004 BC000297 AAH00297 BC082234 BC083514 AAH83514 BT007302 AAP35966 DB074885 DB078662 L25798 AAA62411 M15802 X66435 CAA47061 XM_011514034 XP_011512336 XM_011514035 XP_011512337 XM_011514036 XP_011512338 NM_001098272 NP_001091742 NM_002130 NP_002121
Function This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Subcellular Location Cytoplasm.
Top Pathways Terpenoid backbone biosynthesis, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

cHMGCS CRISPR/Cas9 KO Plasmid (h) - sc-417181 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS HDR Plasmid (h) - sc-417181-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS Double Nickase Plasmid (h) - sc-417181-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS Double Nickase Plasmid (h2) - sc-417181-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS CRISPR Activation Plasmid (h) - sc-417181-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS CRISPR Activation Plasmid (h2) - sc-417181-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS Lentiviral Activation Particles (h) - sc-417181-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS Lentiviral Activation Particles (h2) - sc-417181-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cHMGCS siRNA (h) - sc-44506 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cHMGCS shRNA Plasmid (h) - sc-44506-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cHMGCS shRNA (h) Lentiviral Particles - sc-44506-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HMGCS1 RNAi - H00003157-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU045481 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10167 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10167 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HMGCS1 siRNA (Human) - CRH2154 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HMGCS1 - MBS8226430 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HMGCS1 (NM_002130.7) - SHH313385 from Creative biogene

Category siRNA
Species Reactivities Human

HMGCS1 shRNA Plasmid (Human) - CHH2154 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HMGCS1 miRNA 3'UTR clone - MiUTR3H-01094 from Creative biogene

Species Reactivities Human

HMGCS1 miRNA 3'UTR clone - MiUTR3H-01095 from Creative biogene

Species Reactivities Human
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