| Gene Symbol |
PPP3R1
|
| Entrez Gene |
5534
|
| Alt Symbol |
CALNB1, CNB, CNB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 3, regulatory subunit B, alpha
|
| Other Description |
calcineurin B, type I (19kDa)|calcineurin subunit B type 1|protein phosphatase 2B regulatory subunit 1|protein phosphatase 2B regulatory subunit B alpha|protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I)|protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)|protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform
|
| Swissprots |
B2RC10 P63098 Q53SL0 B5MDU4
|
| Accessions |
AAY14715 EAW99878 P63098 AK307136 AK314893 BAG37407 BC027913 AAH27913 BM468705 BQ228635 CR456938 CAG33219 NM_000945 NP_000936
|
| Function |
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}. Cell membrane, sarcolemma. Note=Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. {ECO:0000250}.
|
| Top Pathways |
Glucagon signaling pathway, Tuberculosis, Glutamatergic synapse, Amphetamine addiction, Oxytocin signaling pathway
|
![Western Blot: Calcineurin B Overexpression Lysate (Adult Normal) [NBL1-14707] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Calcineurin B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3540_Calcineurin%2520B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14707-img0002.jpg)