Gene Symbol | PPP3R1 |
---|---|
Entrez Gene | 5534 |
Alt Symbol | CALNB1, CNB, CNB1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 3, regulatory subunit B, alpha |
Other Description | calcineurin B, type I (19kDa)|calcineurin subunit B type 1|protein phosphatase 2B regulatory subunit 1|protein phosphatase 2B regulatory subunit B alpha|protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I)|protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I)|protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform |
Swissprots | B2RC10 P63098 Q53SL0 B5MDU4 |
Accessions | AAY14715 EAW99878 P63098 AK307136 AK314893 BAG37407 BC027913 AAH27913 BM468705 BQ228635 CR456938 CAG33219 NM_000945 NP_000936 |
Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}. Cell membrane, sarcolemma. Note=Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. {ECO:0000250}. |
Top Pathways | Glucagon signaling pathway, Tuberculosis, Glutamatergic synapse, Amphetamine addiction, Oxytocin signaling pathway |