PRDX1

Gene Symbol	PRDX1
Entrez Gene	5052
Alt Symbol	MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Species	Human
Gene Type	protein-coding
Description	peroxiredoxin 1
Other Description	natural killer cell-enhancing factor A|natural killer-enhancing factor A|peroxiredoxin-1|proliferation-associated gene A|proliferation-associated gene protein|thioredoxin peroxidase 2|thioredoxin-dependent peroxide reductase 2
Swissprots	Q5T155 Q2V576 B5BU26 Q06830 D3DPZ8 P35703 Q5T154
Accessions	ABB84465 CAH59516 EAX06975 EAX06976 EAX06977 EAX06978 EAX06979 EAX06980 EAX06981 EAX06982 Q06830 AB451262 BAG70076 AB451388 BAG70202 AI912389 AK131049 AK311898 BAG34839 AV691526 BC007063 AAH07063 BC021683 AAH21683 BM740381 BM762399 BM787105 BM827394 BT019740 AAV38545 BU564066 CD638470 CR407652 CAG28580 DQ893173 ABM84099 DQ896472 ABM87471 L19184 AAA50464 X67951 CAA48137 NM_001202431 NP_001189360 NM_002574 NP_002565 NM_181696 NP_859047 NM_181697 NP_859048
Function	Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Peroxiredoxin 1 (PRX1) Human ELISA Kit - ab185983 from Abcam Category ELISA Kit Prices $448.00 Sizes 1 x 96 tests Sensitivity 200 pg/ml Range 0.27 ng/ml - 200 ng/ml

Human PRDX1 / Peroxiredoxin 1 ELISA Kit (Sandwich ELISA) - LS-F7204 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse PRDX1 / Peroxiredoxin 1 ELISA Kit (Sandwich ELISA) - LS-F8760 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Rat PRDX1 / Peroxiredoxin 1 ELISA Kit (Sandwich ELISA) - LS-F9467 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 0.156-10 ng/ml

Human PRDX1 / Peroxiredoxin 1 ELISA Kit (Sandwich ELISA) - LS-F12391 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 0.156-10 ng/ml

Mouse PRDX1 / Peroxiredoxin 1 ELISA Kit (Sandwich ELISA) - LS-F12390 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Prx1 ELISA kit - 55R-1877 from Fitzgerald Category ELISA Kit Prices $495.00 Sizes 1 kit

Human Peroxiredoxin 1 ELISA Kit - abx152711 from Abbexa Category ELISA Kit Sensitivity 0.126 ng/ml Range 0.313 ng/ml - 20 ng/ml

Peroxiredoxin 1 (PRDX1), Human, ELISA Kit - SEC749Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.126ng/mL Range 0.312-20ng/mL

Peroxiredoxin-1 (PRDX1), Human, ELISA Kit - CSB-EL018653HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Peroxiredoxin-1, PRDX1, Human, ELISA Kit - E2222h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Peroxiredoxin 1, PRDX1, Human, ELISA Kit - E-EL-H1161 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Peroxiredoxin 1, PRDX1, Rabbit, ELISA Kit - E-EL-RB1407 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Peroxiredoxin 1, PRDX1, Chicken, ELISA Kit - E-EL-Ch0532 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Peroxiredoxin 1, PRDX1, Porcine, ELISA Kit - E-EL-P2065 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Peroxiredoxin 1, PRDX1, Monkey, ELISA Kit - E-EL-MK2234 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

PRDX1 (Human) ELISA kit - KA0536 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Peroxiredoxin 1, ELISA Kit - MBS052276 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS103992 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS081501 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS102756 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS100202 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS085100 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Peroxiredoxin 1, ELISA Kit - MBS084125 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

peroxiredoxin 1, ELISA Kit - MBS928497 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PRDX1 is typically less than 0.78 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 3.12 ng/ml -200 ng/ml.

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