PRDX1

Gene Symbol	PRDX1
Entrez Gene	5052
Alt Symbol	MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Species	Human
Gene Type	protein-coding
Description	peroxiredoxin 1
Other Description	natural killer cell-enhancing factor A|natural killer-enhancing factor A|peroxiredoxin-1|proliferation-associated gene A|proliferation-associated gene protein|thioredoxin peroxidase 2|thioredoxin-dependent peroxide reductase 2
Swissprots	Q5T155 Q2V576 B5BU26 Q06830 D3DPZ8 P35703 Q5T154
Accessions	ABB84465 CAH59516 EAX06975 EAX06976 EAX06977 EAX06978 EAX06979 EAX06980 EAX06981 EAX06982 Q06830 AB451262 BAG70076 AB451388 BAG70202 AI912389 AK131049 AK311898 BAG34839 AV691526 BC007063 AAH07063 BC021683 AAH21683 BM740381 BM762399 BM787105 BM827394 BT019740 AAV38545 BU564066 CD638470 CR407652 CAG28580 DQ893173 ABM84099 DQ896472 ABM87471 L19184 AAA50464 X67951 CAA48137 NM_001202431 NP_001189360 NM_002574 NP_002565 NM_181696 NP_859047 NM_181697 NP_859048
Function	Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Peroxiredoxin 1 full length protein - ab79945 from Abcam Category Protein Prices $302.00 Sizes 50 µg Source Baculovirus Species Human

Active human Peroxiredoxin 1 full length protein - ab167989 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Active human Peroxiredoxin 1 full length protein - ab74172 from Abcam Category Protein Prices $239.00, $883.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human Peroxiredoxin 1 (mutated K197 D) full length protein - ab95476 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Peroxiredoxin 1 (mutated K197 R) full length protein - ab95477 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Peroxiredoxin 1 peptide - ab41919 from Abcam Category Peptide

PRDX1 / Peroxiredoxin 1 Antibody Blocking Peptide - LS-E7206 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDX1 / Peroxiredoxin 1 Antibody Blocking Peptide - LS-E17532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDX1 / Peroxiredoxin 1 Antibody Blocking Peptide - LS-E26916 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Peroxiredoxin 1 Protein - NBC1-18543 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Peroxiredoxin 1 Recombinant Protein - H00005052-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Peroxiredoxin 1 Protein - P3465 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Source E. coli Species Human

Peroxiredoxin 1 Recombinant Protein - P4543 from Novus Biologicals Category Protein Prices $549.00 Sizes 250 µg Species Human

PRDX1-Antibody-Center-Blocking-Peptide - BP2924c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRX I blocking peptide - GTX88526-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

PRRX1 blocking peptide - GTX88910-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

Recombinant human Peroxiredoxin-1 (OPCA00373) - OPCA00373 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

PRDX1 Protein (OPPA01692) - OPPA01692 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human PRDX1 His tag protein - orb83504 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human PAGA protein - orb245068 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human PRDX1 protein - orb90242 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli Species Human

Peroxiredoxin I protein - 30R-2986 from Fitzgerald Category Protein Prices $245.00 Sizes 250 µg Source E.coli

PRDX1 Blocking Peptide - 33R-8807 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PRDX1 protein (His Tag) - 80R-1854 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human Peroxiredoxin 1 Protein - abx068475 from Abbexa Category Protein Source E.coli Species Human

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