| Gene Symbol |
TACR2
|
| Entrez Gene |
6865
|
| Alt Symbol |
NK2R, NKNAR, SKR, TAC2R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tachykinin receptor 2
|
| Other Description |
NK-2 receptor|NK-2R|neurokinin 2 receptor|neurokinin A receptor|seven transmembrane helix receptor|substance K receptor|substance-K receptor
|
| Swissprots |
Q8NGQ8 A8K7I1 Q9UDE6 Q4QRI5 Q9UDE7 P21452
|
| Accessions |
AAA60347 AAB05897 AAK51938 BAC05952 EAW54324 EAW54325 P21452 AK096906 AK291996 BAF84685 AK300649 BAG62337 AY322545 AAP84358 BC033742 BC096842 AAH96842 DA929480 FJ200479 ACO54876 M57414 AAC31760 NM_001057 NP_001048
|
| Function |
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. {ECO:0000269|PubMed:1659297}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|