TACR2

Gene Symbol	TACR2
Entrez Gene	6865
Alt Symbol	NK2R, NKNAR, SKR, TAC2R
Species	Human
Gene Type	protein-coding
Description	tachykinin receptor 2
Other Description	NK-2 receptor|NK-2R|neurokinin 2 receptor|neurokinin A receptor|seven transmembrane helix receptor|substance K receptor|substance-K receptor
Swissprots	Q8NGQ8 A8K7I1 Q9UDE6 Q4QRI5 Q9UDE7 P21452
Accessions	AAA60347 AAB05897 AAK51938 BAC05952 EAW54324 EAW54325 P21452 AK096906 AK291996 BAF84685 AK300649 BAG62337 AY322545 AAP84358 BC033742 BC096842 AAH96842 DA929480 FJ200479 ACO54876 M57414 AAC31760 NM_001057 NP_001048
Function	This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. {ECO:0000269|PubMed:1659297}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NK-2R CRISPR/Cas9 KO Plasmid (h) - sc-403149 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R HDR Plasmid (h) - sc-403149-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R Double Nickase Plasmid (h) - sc-403149-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R Double Nickase Plasmid (h2) - sc-403149-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R CRISPR Activation Plasmid (h) - sc-403149-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R CRISPR Activation Plasmid (h2) - sc-403149-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R Lentiviral Activation Particles (h) - sc-403149-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R Lentiviral Activation Particles (h2) - sc-403149-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R siRNA (h) - sc-42292 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK-2R shRNA Plasmid (h) - sc-42292-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK-2R shRNA (h) Lentiviral Particles - sc-42292-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK2R RNAi - H00006865-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU048521 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20954 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20954 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TACR2 siRNA (Human) - CRH4694 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TACR2 - MBS8233884 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NK-2R HDR Plasmid (h2) - sc-403149-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-2R CRISPR/Cas9 KO Plasmid (h2) - sc-403149-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human TACR2 (NM_001057.2) - SHH422472 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TACR2(NM_001057.2) - SHL053680 from Creative biogene Category siRNA Species Reactivities Human

Human TACR2 siRNA - orb265196 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TACR2 shRNA Plasmid (Human) - CHH4694 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TACR2 miRNA 3'UTR clone - MiUTR1H-10148 from Creative biogene Species Reactivities Human

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