Gene Symbol | TACR2 |
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Entrez Gene | 6865 |
Alt Symbol | NK2R, NKNAR, SKR, TAC2R |
Species | Human |
Gene Type | protein-coding |
Description | tachykinin receptor 2 |
Other Description | NK-2 receptor|NK-2R|neurokinin 2 receptor|neurokinin A receptor|seven transmembrane helix receptor|substance K receptor|substance-K receptor |
Swissprots | Q8NGQ8 A8K7I1 Q9UDE6 Q4QRI5 Q9UDE7 P21452 |
Accessions | AAA60347 AAB05897 AAK51938 BAC05952 EAW54324 EAW54325 P21452 AK096906 AK291996 BAF84685 AK300649 BAG62337 AY322545 AAP84358 BC033742 BC096842 AAH96842 DA929480 FJ200479 ACO54876 M57414 AAC31760 NM_001057 NP_001048 |
Function | This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. {ECO:0000269|PubMed:1659297}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
TACR2 / NK2R Antibody Blocking Peptide - LS-E28944 from LifeSpan Bioscience
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TACR2 / NK2R Antibody Blocking Peptide - LS-E28945 from LifeSpan Bioscience
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TACR2 / NK2R Antibody Blocking Peptide - LS-E28215 from LifeSpan Bioscience
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TACR2 / NK2R Antibody Blocking Peptide - LS-E28216 from LifeSpan Bioscience
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TACR2 / NK2R Antibody Blocking Peptide - LS-E28218 from LifeSpan Bioscience
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TACR2 / NK2R Antibody Blocking Peptide - LS-E26642 from LifeSpan Bioscience
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Neurokinin 2 Receptor blocking peptide - GTX88795-PEP from GeneTex
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Human Tachykinin Receptor 2 Protein - abx069226 from Abbexa
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Tachykinin Receptor 2 Peptide - AC21-1478-P from Abcore
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NK2 Receptor Peptide - 46-717P from ProSci
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Recombinant Tachykinin Receptor 2 (TACR2) - RPA618Hu01 from Uscn Life Science Inc.
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Recombinant Tachykinin Receptor 2 (TACR2) - RPA618Mu01 from Uscn Life Science Inc.
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Recombinant Tachykinin Receptor 2 (TACR2) - RPA618Ra01 from Uscn Life Science Inc.
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ChemiSCREEN™ Membrane Preparation Recombinant Human NK 2 Tachykinin Receptor - HTS144M from EMD Millipore
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NK-2R (P340) Peptide - BS2633P from Bioworld Technology
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Recombinant Tachykinin Receptor 2 (TACR2) - RPA618Hu01 from Cloud-clone
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Tachykinin Receptor 2 (TACR2) - RPU143942 from Biomatik
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TACR2 Peptide - abx164740 from Abbexa
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Tachykinin Receptor 2, Recombinant Protein - MBS2028928 from MyBioSource
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Tachykinin Receptor 2 (TACR2), Recombinant Protein - MBS2018773 from MyBioSource
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Neurokinin 2 Receptor, Peptide - MBS659681 from MyBioSource
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TACR2/Neurokinin 2 receptor, Peptide - MBS426360 from MyBioSource
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TACR2 Peptide, Human - M34GP15534H from Creative Peptides
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Recombinant Tachykinin Receptor 2 (TACR2) - RPU43942 from Biomatik
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TACR2 Recombinant Protein (OPCD07266) - OPCD07266 from Aviva Systems Biology
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