Gene Symbol | PSMA2 |
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Entrez Gene | 5683 |
Alt Symbol | HC3, MU, PMSA2, PSC2 |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) subunit, alpha type, 2 |
Other Description | macropain subunit C3|multicatalytic endopeptidase complex subunit C3|proteasome component C3|proteasome subunit HC3|proteasome subunit alpha type-2 |
Swissprots | P25787 Q9BU45 Q6ICS6 |
Accessions | CBF59431 CBU84675 EAL24005 EAW94151 EAW94152 EAW94153 P25787 AK222976 BAD96696 AK290654 BAF83343 AU120930 BC002900 AAH02900 BC047697 AAH47697 BX641097 CAE46046 CB990982 CR450317 CAG29313 D00760 BAA00657 HQ448587 ADQ33065 NM_002787 NP_002778 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation. |
Subcellular Location | Cytoplasm. Nucleus. Cytoplasm, P-body {ECO:0000250}. Note=Colocalizes with TRIM5 in the cytoplasmic bodies. {ECO:0000250}. |
Top Pathways | Proteasome |
Human Proteasome 20S alpha 2 full length protein - ab116173 from Abcam
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PSMA2 Antibody Blocking Peptide - LS-E20497 from LifeSpan Bioscience
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PSMA2 Antibody Blocking Peptide - LS-E20496 from LifeSpan Bioscience
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Proteasome 20S alpha 2 Recombinant Protein - H00005683-P01 from Novus Biologicals
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Recombinant Human Proteasome 20S alpha 2 Protein - NBP1-72473 from Novus Biologicals
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PSMA2-Antibody-C-term-Blocking-Peptide - BP2913b from Abgent, a WuXi AppTec company
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PSMA2-Antibody-N-term-Blocking-Peptide - BP6824d from Abgent, a WuXi AppTec company
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PSMA2-Antibody-C-term-Blocking-Peptide - BP6824b from Abgent, a WuXi AppTec company
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PSMA2-Antibody-N-term-Blocking-Peptide - BP6824a from Abgent, a WuXi AppTec company
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Human PSMA2 protein - orb169087 from Biorbyt
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PSMA2 Blocking Peptide - 33R-9560 from Fitzgerald
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PSMA2 protein (His tag) - 80R-1987 from Fitzgerald
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PSMA2 (1-234, His-tag) - AR50056PU-N from Acris Antibodies
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PSMA2 (1-234, His-tag) - AR50056PU-S from Acris Antibodies
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PSMA2 - H00005683-P01-10 from Acris Antibodies
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PSMA2 - H00005683-P01-25 from Acris Antibodies
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PSMA2, 1-234aa, Human, His tag, E.coli - 01-2011-2 from ARP American Research Products
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PSMA2 fusion protein - ag5753 from Proteintech Group
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PSMA2 fusion protein - ag5837 from Proteintech Group
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PSMA2 Human - ENPS-182 from NeoScientific
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Recombinant Human Proteasome Subunit Alpha Type 2 Enzyme - BP002726-ENZ-175 from Syd Labs
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PSMA2, 1-234aa, Recombinant Protein - GWB-P0807A from Genway Biotech
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Recombinant Human PSMA2, His-tagged - PSMA2-30429TH from Creative Biomart
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Recombinant Human PSMA2, His-tagged - PSMA2-31102TH from Creative Biomart
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Recombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 2, His-tagged - PSMA2-6877H from Creative Biomart
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