Gene Symbol | DPM2 |
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Entrez Gene | 8818 |
Alt Symbol | CDG1U |
Species | Human |
Gene Type | protein-coding |
Description | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
Other Description | DPM synthase complex subunit|DPM synthase subunit 2|dolichol phosphate-mannose biosynthesis regulatory protein|dolichol-phosphate mannose synthase subunit 2 |
Swissprots | O94777 Q6FGH3 Q5XKK9 |
Accessions | O94777 AB013361 BAA33974 AB451329 BAG70143 AB451473 BAG70287 AF061729 AAG43140 AI954002 AK312121 BAG35057 BC015233 AAH15233 BC015374 AAH15374 BC048256 BC107863 AAI07864 CR542134 CAG46931 NM_003863 NP_003854 NM_152690 |
Function | Regulates the biosynthesis of dolichol phosphate- mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. {ECO:0000269|PubMed:10944123}. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Top Pathways | N-Glycan biosynthesis, Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
DPM2 Antibody Blocking Peptide - LS-E26883 from LifeSpan Bioscience
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DPM2 Antibody Blocking Peptide - LS-E26884 from LifeSpan Bioscience
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DPM2-Antibody-C-term-Blocking-Peptide - BP16844b from Abgent, a WuXi AppTec company
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DPM2 blocking peptide - GTX47576-PEP from GeneTex
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DPM2 Peptide - AC21-1718-P from Abcore
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DPM2 Peptide - 42-141P from ProSci
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DPM2 fusion protein - ag8044 from Proteintech Group
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DPM2 fusion protein - ag3003 from Proteintech Group
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Recombinant Human DPM2 - DPM2-652H from Creative Biomart
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DPM2 - TP303919 from Acris Antibodies
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DPM2, Peptide - MBS426363 from MyBioSource
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DPM2 Recombinant Protein Antigen - NBP2-38056PEP from Novus Biologicals
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DPM2 Peptide, Human - M34GP04512H from Creative Peptides
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Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2), Recombinant Protein - MBS1067140 from MyBioSource
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Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2), Recombinant Protein - MBS7013851 from MyBioSource
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DPM2 Immunizing peptide - orb59530 from Biorbyt
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