Gene Symbol | PJA1 |
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Entrez Gene | 64219 |
Alt Symbol | PRAJA1, RNF70 |
Species | Human |
Gene Type | protein-coding |
Description | praja ring finger 1, E3 ubiquitin protein ligase |
Other Description | E3 ubiquitin-protein ligase Praja-1|RING finger protein 70|praja 1 |
Swissprots | Q9HAC1 Q5JUT9 Q5JUT8 A2A322 Q8NG27 Q8NG28 |
Accessions | EAX05367 EAX05368 EAX05369 Q8NG27 AF262024 AAM53039 AF264620 AAM53040 AK021892 BAB13928 AK096611 BAG53338 AK226171 AK290543 BAF83232 AK293266 BAG56796 AK294632 BAG57811 BC039149 BC048323 AAH48323 BC058327 BC075803 AAH75803 BC105051 AAI05052 BC105053 AAI05054 BC113035 AAI13036 BM127146 DA778001 DC349747 EU446995 ABZ92524 XM_005262292 XP_005262349 XM_011531011 XP_011529313 NM_001032396 NP_001027568 NM_022368 NP_071763 NM_145119 NP_660095 |
Function | Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting. {ECO:0000250, ECO:0000269|PubMed:12036302}. |
Tissue Specificity | Expressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex. {ECO:0000269|PubMed:12036302}. |
Active human RNF70 full length protein - ab125812 from Abcam
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Human RNF70 peptide - ab23047 from Abcam
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PJA1 / PRAJA1 Antibody Blocking Peptide - LS-E3608 from LifeSpan Bioscience
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PJA1 / PRAJA1 Antibody Blocking Peptide - LS-E27866 from LifeSpan Bioscience
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Recombinant Human RNF70 Protein - H00064219-Q01 from Novus Biologicals
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PJA1-Antibody-N-term-Blocking-Peptide - BP14811a from Abgent, a WuXi AppTec company
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PJA1 blocking peptide - GTX24540-PEP from GeneTex
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RNF70 Peptide - AC21-2873-P from Abcore
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PJA1 / RNF70 - H00064219-Q01-10 from Acris Antibodies
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PJA1 / RNF70 - H00064219-Q01-25 from Acris Antibodies
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PJA1 Peptide - 43-019P from ProSci
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PJA1 Peptide - 8069P from ProSci
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PJA1 fusion protein - ag11742 from Proteintech Group
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PJA1 fusion protein - Ag11820 from Proteintech Group
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Recombinant Human PJA1, SUMO-tagged - PJA1-114H from Creative Biomart
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Recombinant Human E3 ubiquitin-protein ligase Praja-1(PJA1) - CSB-YP844051HU CSB-EP844051HU CSB-BP844051HU CSB-MP844051HU from Cusabio
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Praja-1/RNF70, Peptide - MBS427759 from MyBioSource
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RNF70 Recombinant Protein Antigen - NBP1-87399PEP from Novus Biologicals
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PJA-Antibody-Center-Blocking-Peptide - BP2102c from Abgent, a WuXi AppTec company
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PJA1 Peptide, Human - M34GP11832H from Creative Peptides
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E3 ubiquitin-protein ligase Praja-1 (PJA1), Recombinant Protein - MBS1290494 from MyBioSource
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