EP400

Gene Symbol EP400
Entrez Gene 57634
Alt Symbol CAGH32, P400, TNRC12
Species Human
Gene Type protein-coding
Description E1A binding protein p400
Other Description CAG repeat protein 32|E1A-binding protein p400|domino homolog|hDomino|p400 SWI2/SNF2-related protein|p400 kDa SWI2/SNF2-related protein|trinucleotide repeat containing 12|trinucleotide repeat-containing gene 12 protein
Swissprots Q8NE05 O15411 Q96L91 Q96JK7 Q9P230 Q8N8Q7 Q6P2F5
Accessions EAW98534 EAW98535 EAW98536 Q96L91 AB040931 BAA96022 AB058721 BAB47447 AK025040 AK074395 AK096311 BAC04759 AK097299 AK124012 AK127058 AL832718 AW376113 AY044869 AAK97789 BC016068 BC037208 AAH37208 BC064554 AAH64554 BC150291 AAI50292 BX369075 DA450209 JF432826 ADZ16043 U80743 AAB91441 NM_015409 NP_056224
Function Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. {ECO:0000269|PubMed:14966270, ECO:0000269|PubMed:24463511}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00549}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11509179}.

p400 (C-16) - sc-66497 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p400 (C-16): sc-66497. Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing nuclear staining of neuronal cells and glial cells.

p400 (H-141) - sc-292106 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

p400 (S-20) - sc-66500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-p400 antibody - ab5201 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab5201 stained human HeLa cells. The cells were PFA fixed (3.7% PFA, 10 min) and incubated with the antibody (ab5201, 1µg/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). Alexa Fluor® 594 WGA was used to label plasma membranes (red).

Anti-p400 antibody - ChIP Grade - ab70301 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-p400 antibody - ChIP Grade (ab70301) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µg

Anti-EP400 / p400 Antibody (C-Terminus) - LS-C92962 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-EP400 / p400 Antibody (aa743-851) - LS-C307929 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EP400 / p400 Antibody - LS-C307947 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-EP400 / p400 Antibody (C-Terminus) - LS-C287423 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse p400 by Western Blot. Samples: Whole cell lysate from CT26.WT (15 and 50 ug) cells. Antibodies: Affinity purified rabbit anti-p400 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

p400 Antibody - NB200-210 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: p400 Antibody [NB200-210] - Whole cell lysate from CT26.WT (15 and 50 ug) cells. Antibodies: Affinity purified rabbit anti-p400 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes

p400 Antibody - NBP1-88230 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: p400 Antibody [NBP1-88230] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus.

p400 Antibody - NBP2-19663 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: p400 Antibody [NBP2-19663] - Sample (30 ug of whole cell lysate) A: MCF-7 7. 5% SDS PAGE gel, diluted at 1:1000.

p400 Antibody - H00057634-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

p400 Antibody (2A7) - H00057634-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A7
Western Blot: p400 Antibody (2A7) [H00057634-M01] - Analysis of EP400 expression in transfected 293T cell line by EP400 monoclonal antibody (M01), clone 2A7.Lane 1: EP400 transfected lysate(105.7 KDa).Lane 2: Non-transfected lysate.

p400 Polyclonal Antibody - bs-8279R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EP400 antibody produced in mouse - SAB1407798 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-EP400: <B>Cat. No. SAB1407798</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Monoclonal Anti-EP400 antibody produced in mouse - SAB1402613 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A7
<B>Immunoblotting</B><BR/>Monoclonal Anti-EP400, antibody produced in mouse, clone 2A7, purified immunoglobulin: <B>Cat. No. SAB1402613</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.99 kDa using immunogen protein lysate.

Anti-EP400 antibody produced in rabbit - HPA016704 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-EP400: <B>Cat. No. HPA016704</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human gall bladder shows strong nuclear positivity in glandular cells.

p400 antibody [N1], N-term - GTX116689 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-p400 antibody [N1], N-term used in ICC/IF. GTX116689
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