| Gene Symbol |
TMEM123
|
| Entrez Gene |
114908
|
| Alt Symbol |
KCT3, PORIMIN, PORMIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 123
|
| Other Description |
KCT-3|keratinocytes associated transmembrane protein 3|keratinocytes-associated transmembrane protein 3|porimin|pro oncosis receptor inducing membrane injury|pro-oncosis receptor inducing membrane injury|serine/threonine-rich receptor
|
| Swissprots |
Q8N131 Q96QV2 Q8IWS2
|
| Accessions |
CAI72111 EAW67019 EAW67020 EAW67021 Q8N131 AJ293406 AK026572 AK075420 BAC11610 AK225790 AL050161 AL110202 AL137643 AY008283 AAG21694 AY157580 AAO13164 AY358696 AAQ89059 BC032296 AAH32296 DB146474 DQ891654 ABM82580 DQ894842 ABM85768 NM_052932 NP_443164
|
| Function |
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. {ECO:0000269|PubMed:11481458}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. {ECO:0000269|PubMed:11481458, ECO:0000269|PubMed:12752121}.
|