Gene Symbol | TMEM123 |
---|---|
Entrez Gene | 114908 |
Alt Symbol | KCT3, PORIMIN, PORMIN |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 123 |
Other Description | KCT-3|keratinocytes associated transmembrane protein 3|keratinocytes-associated transmembrane protein 3|porimin|pro oncosis receptor inducing membrane injury|pro-oncosis receptor inducing membrane injury|serine/threonine-rich receptor |
Swissprots | Q8N131 Q96QV2 Q8IWS2 |
Accessions | CAI72111 EAW67019 EAW67020 EAW67021 Q8N131 AJ293406 AK026572 AK075420 BAC11610 AK225790 AL050161 AL110202 AL137643 AY008283 AAG21694 AY157580 AAO13164 AY358696 AAQ89059 BC032296 AAH32296 DB146474 DQ891654 ABM82580 DQ894842 ABM85768 NM_052932 NP_443164 |
Function | Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. {ECO:0000269|PubMed:11481458}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. {ECO:0000269|PubMed:11481458, ECO:0000269|PubMed:12752121}. |
Porimin CRISPR/Cas9 KO Plasmid (h) - sc-414056 from Santa Cruz Biotechnology
|
||||||||
Porimin HDR Plasmid (h) - sc-414056-HDR from Santa Cruz Biotechnology
|
||||||||
Porimin Double Nickase Plasmid (h) - sc-414056-NIC from Santa Cruz Biotechnology
|
||||||||
Porimin Double Nickase Plasmid (h2) - sc-414056-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Porimin CRISPR Activation Plasmid (h) - sc-414056-ACT from Santa Cruz Biotechnology
|
||||||||
Porimin CRISPR Activation Plasmid (h2) - sc-414056-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Porimin Lentiviral Activation Particles (h) - sc-414056-LAC from Santa Cruz Biotechnology
|
||||||||
Porimin Lentiviral Activation Particles (h2) - sc-414056-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Porimin siRNA (h) - sc-61383 from Santa Cruz Biotechnology
|
||||||||
Porimin shRNA Plasmid (h) - sc-61383-SH from Santa Cruz Biotechnology
|
||||||||
Porimin shRNA (h) Lentiviral Particles - sc-61383-V from Santa Cruz Biotechnology
|
||||||||
Porimin RNAi - H00114908-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU083171 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21487 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21487 from Sigma-Aldrich
|
||||||||
TMEM123 siRNA (Human) - CRJ4415 from Cohesion Biosciences
|
||||||||
TMEM123 - MBS8235559 from MyBioSource
|
||||||||
shRNA set against Human TMEM123 (NM_052932.2) - SHH428924 from Creative biogene
|
||||||||
shRNA set against Human TMEM123(NM_052932.2) - SHL076482 from Creative biogene
|
||||||||
Human TMEM123 siRNA - orb274916 from Biorbyt
|
||||||||
TMEM123 shRNA Plasmid (Human) - CHJ4415 from Cohesion Biosciences
|
||||||||
TMEM123 miRNA 3'UTR clone - MiUTR1H-10486 from Creative biogene
|