LEMD3

Gene Symbol LEMD3
Entrez Gene 23592
Alt Symbol MAN1
Species Human
Gene Type protein-coding
Description LEM domain containing 3
Other Description LEM domain-containing protein 3|inner nuclear membrane protein Man1|integral inner nuclear membrane protein
Swissprots Q9Y2U8 Q9NT47 Q9NYA5
Accessions AAF73293 EAW97148 EAW97149 Q9Y2U8 AF112299 AAD31593 AK024954 AK295406 BAG58357 AK304317 BAG65169 AK312473 AL137533 CAB70796 BC167864 AAI67864 BX390128 NM_001167614 NP_001161086 NM_014319 NP_055134
Function Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest. {ECO:0000269|PubMed:15601644, ECO:0000269|PubMed:15647271}.
Subcellular Location Nucleus inner membrane {ECO:0000269|PubMed:15647271}; Multi-pass membrane protein {ECO:0000269|PubMed:15647271}.
Tissue Specificity Heart, brain, placenta, lung, liver and skeletal muscle.

MAN1 CRISPR/Cas9 KO Plasmid (h) - sc-404258 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 HDR Plasmid (h) - sc-404258-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 Double Nickase Plasmid (h) - sc-404258-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 Double Nickase Plasmid (h2) - sc-404258-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 CRISPR Activation Plasmid (h) - sc-404258-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 CRISPR Activation Plasmid (h2) - sc-404258-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 Lentiviral Activation Particles (h) - sc-404258-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 Lentiviral Activation Particles (h2) - sc-404258-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAN1 siRNA (h) - sc-43384 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAN1 shRNA Plasmid (h) - sc-43384-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAN1 shRNA (h) Lentiviral Particles - sc-43384-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU137121 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11642 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11642 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LEMD3 siRNA (Human) - CRH8382 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LEMD3 (NM_014319.4) - SHH329531 from Creative biogene

Category siRNA
Species Reactivities Human

Human LEMD3 siRNA - orb268884 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LEMD3 shRNA Plasmid (Human) - CHH8382 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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