KCND3

Gene Symbol KCND3
Entrez Gene 3752
Alt Symbol KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated Shal related subfamily D, member 3
Other Description potassium ionic channel Kv4.3|potassium voltage-gated channel subfamily D member 3|potassium voltage-gated channel, Shal-related subfamily, member 3|sha1-related potassium channel Kv4.3|voltage-gated K+ channel|voltage-gated potassium channel subunit Kv4.3
Swissprots Q9UH85 Q5T0M0 O60576 Q9UK17 O60577 Q9UH86 Q9UK16 Q14D71
Accessions AAF68177 AAF68178 EAW56510 EAW56511 EAW56512 Q9UK17 AF048712 AAC05121 AF048713 AAC05122 AF120491 AAD38898 AF187963 AAF01044 AF187964 AAF01045 AF205856 AAF20924 AF205857 AAF20925 AY863198 AAX58111 BC113475 AAI13476 BC113477 AAI13478 BC143390 AAI43391 HQ258336 ADR83090 XM_005270851 XP_005270908 XM_006710629 XP_006710692 XM_006710630 XP_006710693 XM_006710631 XP_006710694 XM_006710632 XP_006710695 XM_011541425 XP_011539727 XM_011541426 XP_011539728 XM_011541427 XP_011539729 XM_011541428 XP_011539730 NM_004980 NP_004971 NM_172198 NP_751948
Function Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. {ECO:0000269|PubMed:10200233, ECO:0000269|PubMed:9843794}.
Subcellular Location Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma {ECO:0000250}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:10200233, ECO:0000269|PubMed:10729221, ECO:0000269|PubMed:9843794}.

KV4.3 (C-17) - sc-11686 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KV4.3 (C-17): sc-11686. Western blot analysis of KV4.3 expression in mouse brain extract.

KV4.3 (N-15) - sc-11684 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Kv4.3 antibody - ab65794 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Kv4.3 antibody - ab49348 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Kv4.3 antibody (ab49348) at 1.25 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG 1/50,000 -1/100,000

Anti-Kv4.3 antibody - ab123347 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Kv4.3 antibody (ab123347) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-Kv4.3 antibody [S75-41] - ab99045 from Abcam

Prices $387.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-41
ab99045 staining Kv4.3 in Mouse cerebellum tissue sections by Immunohistochemistry.

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, Atto 594) - LS-C228337 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa424-473) - LS-C31353 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, Atto 680) - LS-C228338 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, Atto 655) - LS-C228339 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, AP) - LS-C228341 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, Atto 700) - LS-C228340 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, Biotin) - LS-C228342 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (clone S75-41) - LS-C150429 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41
IHC analysis of Kv4.3 using KCND3 / Kv4.3 antibody tested on mouse cerebellum. Neurons appear to be positive on the membrane and slightly in the cytoplasm. Positivity on the fibers as well. Negative white matter.

Anti-KCND3 / Kv4.3 Antibody (aa432-481) - LS-C110041 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCND3 / Kv4.3 antibody LS-C110041 Western blot of HepG2 cell lysate.

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, FITC) - LS-C228345 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, PE-Atto 594) - LS-C229944 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa13-41, AP) - LS-C260899 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, APC) - LS-C228343 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, SA) - LS-C229947 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, PerCP) - LS-C229945 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa13-41, APC) - LS-C260901 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCND3 / Kv4.3 Antibody (aa415-636, clone S75-41, RPE) - LS-C229946 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S75-41

Anti-KCND3 / Kv4.3 Antibody (aa13-41, Biotin) - LS-C260900 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCND3 / Kv4.3 Antibody (aa13-41) - LS-C165418 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KCND3 Antibody western blot of CEM cell line lysates (35 ug/lane). The KCND3 antibody detected the KCND3 protein (arrow).
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