PLOD2

Gene Symbol	PLOD2
Entrez Gene	5352
Alt Symbol	BRKS2, LH2, TLH
Species	Human
Gene Type	protein-coding
Description	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Other Description	lysine hydroxylase 2|lysyl hydroxlase 2|lysyl hydroxylase 2|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2|telopeptide lysyl hydroxylase
Swissprots	O00469 B3KWS3 Q8N170 Q59ED2
Accessions	AAD40977 AAK20119 EAW78939 EAW78940 EAW78941 O00469 AB209879 BAD93116 AK125700 BAG54235 AK130098 AK295084 BAG58125 AL832238 BC016834 AAH16834 BC037169 AAH37169 BM724669 BX537521 U84573 AAB58363 XM_005247535 XP_005247592 XM_005247536 XP_005247593 NM_000935 NP_000926 NM_182943 NP_891988
Function	Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Subcellular Location	Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Tissue Specificity	Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. {ECO:0000269|PubMed:10372558}.
Top Pathways	Lysine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LLH2 CRISPR/Cas9 KO Plasmid (h) - sc-408031 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 HDR Plasmid (h) - sc-408031-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 Double Nickase Plasmid (h) - sc-408031-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 Double Nickase Plasmid (h2) - sc-408031-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 CRISPR Activation Plasmid (h) - sc-408031-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 CRISPR Activation Plasmid (h2) - sc-408031-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 Lentiviral Activation Particles (h) - sc-408031-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 Lentiviral Activation Particles (h2) - sc-408031-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LLH2 siRNA (h) - sc-60950 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LLH2 shRNA Plasmid (h) - sc-60950-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LLH2 shRNA (h) Lentiviral Particles - sc-60950-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Lysine Hydroxylase 2/PLOD2 RNAi - H00005352-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Lysine Hydroxylase 2/PLOD2 RNAi - H00005352-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU092311 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16994 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16994 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

PLOD2 siRNA (Human) - CRH3591 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PLOD2 (NM_182943.2) - SHH377988 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PLOD2(NM_000935.2) - SHR123078 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PLOD2(NM_182943.2) - SHR123096 from Creative biogene Category siRNA Species Reactivities Human

Human PLOD2 siRNA - orb264093 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PLOD2 shRNA Plasmid (Human) - CHH3591 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PLOD2 miRNA 3'UTR clone - MiUTR1H-08011 from Creative biogene Species Reactivities Human

PLOD2 miRNA 3'UTR clone - MiUTR1H-08012 from Creative biogene Species Reactivities Human

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