PLOD2

Gene Symbol PLOD2
Entrez Gene 5352
Alt Symbol BRKS2, LH2, TLH
Species Human
Gene Type protein-coding
Description procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Other Description lysine hydroxylase 2|lysyl hydroxlase 2|lysyl hydroxylase 2|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2|telopeptide lysyl hydroxylase
Swissprots O00469 B3KWS3 Q8N170 Q59ED2
Accessions AAD40977 AAK20119 EAW78939 EAW78940 EAW78941 O00469 AB209879 BAD93116 AK125700 BAG54235 AK130098 AK295084 BAG58125 AL832238 BC016834 AAH16834 BC037169 AAH37169 BM724669 BX537521 U84573 AAB58363 XM_005247535 XP_005247592 XM_005247536 XP_005247593 NM_000935 NP_000926 NM_182943 NP_891988
Function Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Subcellular Location Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Tissue Specificity Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. {ECO:0000269|PubMed:10372558}.
Top Pathways Lysine degradation

LLH2 (N-15) - sc-50067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LLH2 (S-13) - sc-50068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PLOD2 antibody - ab72939 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PLOD2 antibody (ab72939) at 1 µg/ml + human kidney tissue lysate at 25 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-PLOD2 antibody - ab90088 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human bronchial epithelial tissue labelling PLOD2 with ab90088 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - PLOD2. Right - Merge.

Anti-PLOD2 antibody - ab182034 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLOD2 antibody - C-terminal - ab180042 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PLOD2 antibody - C-terminal (ab180042) at 1/1000 dilution + HeLa cell lysate at 35 µg

Anti-PLOD2 Antibody - LS-C332025 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PLOD2 Antibody (aa483-512) - LS-C203782 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PLOD2 Antibody western blot of HeLa cell line lysates (35 ug/lane). The PLOD2 antibody detected the PLOD2 protein (arrow).

Anti-PLOD2 Antibody (C-Terminus) - LS-C345695 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PLOD2 Antibody with human HepG2 Whole Cell lysate.

Anti-PLOD2 Antibody (aa359-640, clone 6D1) - LS-C338679 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6D1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLOD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLOD2.

Anti-PLOD2 Antibody (aa359-640, clone 1A12) - LS-C338665 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLOD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLOD2.

Anti-PLOD2 Antibody (aa359-640, clone 8A4) - LS-C338748 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8A4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLOD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLOD2.

Anti-PLOD2 Antibody - LS-C346148 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using PLOD2 antibody. Blue: DAPI for nuclear staining.

Anti-PLOD2 Antibody (aa359-640, clone 7G5) - LS-C338681 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7G5
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PLOD2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-PLOD2 Antibody (aa467-516) IHC-plus™ - LS-B9694 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PLOD2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9694 concentration 5 ug/ml.

Lysine Hydroxylase 2/PLOD2 Antibody - H00005352-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Lysine Hydroxylase 2/PLOD2 Antibody [H00005352-B01P] - Analysis of PLOD2 expression in human kidney.

Lysine Hydroxylase 2/PLOD2 Antibody - H00005352-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Lysine Hydroxylase 2/PLOD2 Antibody [H00005352-D01] - Expression in transfected 293T cell line. Lane 1: PLOD2 transfected lysate(87.10 KDa). Lane 2: Non-transfected lysate.

Lysine Hydroxylase 2/PLOD2 Antibody - NBP1-58004 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Lysine Hydroxylase 2/PLOD2 Antibody [NBP1-58004] - Titration: 0.2-1 ug/ml, Positive Control: DU145 cell lysate.

Lysine Hydroxylase 2/PLOD2 Antibody (408105) [Unconjugated] - MAB4445 from Novus Biologicals

Prices $99.00, $269.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 408105

Lysine Hydroxylase 2/PLOD2 Antibody - 22440002 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lysine Hydroxylase 2/PLOD2 Antibody [22440002] - Western Blot was performed using affinity purified SEQer PLOD2 antibody. The lanes contain 5-30ug of a whole cell extract. Final concentration of antibodies = 0.1ug/ml (1:10,000 dilution).

Lysine Hydroxylase 2/PLOD2 Antibody - H00005352-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lysine Hydroxylase 2/PLOD2 Antibody [H00005352-D01P] - Analysis of PLOD2 expression in HeLa.

Anti-PLOD2 antibody produced in rabbit - SAB1410976 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLOD2: <B>Cat. No. SAB1410976</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~84.7 kDa using HeLa lysate.

Anti-PLOD2 antibody produced in mouse - SAB1400213 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-PLOD2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400213</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

PLOD2 antibody - middle region (ARP42731_P050) - ARP42731_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLOD2 Antibody - C-terminal region (ARP74135_P050) - ARP74135_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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