FBP1

Gene Symbol	FBP1
Entrez Gene	2203
Alt Symbol	FBP
Species	Human
Gene Type	protein-coding
Description	fructose-1,6-bisphosphatase 1
Other Description	D-fructose-1,6-bisphosphate 1-phosphohydrolase 1|FBPase 1|fructose-bisphosphatase 1|growth-inhibiting protein 17|liver FBPase
Swissprots	P09467 Q53F94 Q96E46 O75571
Accessions	AAC50207 AAW34363 BAF91908 CBF86692 CBG16870 CBV02277 CBV30316 EAW92617 P09467 AF073475 AAC25774 AK223395 BAD97115 AK292199 BAF84888 AK316583 BAG38171 AY544122 AAT11153 BC012927 AAH12927 D26054 BAA05051 D26055 BAA05052 D26056 BAA05053 DA962803 L10320 AAA35817 M19922 AAA35517 U47918 AAA89097 U47919 AAA89098 XM_006717005 XP_006717068 NM_000507 NP_000498 NM_001127628 NP_001121100
Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. {ECO:0000269|PubMed:16497803, ECO:0000269|PubMed:18375435, ECO:0000269|PubMed:22517657}.
Tissue Specificity	Expressed in pancreatic islets. {ECO:0000269|PubMed:18375435}.
Top Pathways	Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Insulin signaling pathway, AMPK signaling pathway, Glucagon signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Folate Receptor 1, Adult (FOLR1), Human, ELISA Kit - SEF460Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 5.8pg/mL Range 15.6-1,000pg/mL

Folate receptor alpha (FOLR1), Human, ELISA Kit - CSB-EL008784HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Fructose-1, 6-bisphosphatase 1 (FBP1), Human, ELISA Kit - E01F0362 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Ras-related protein Rab-14 (RAB14), Human, ELISA Kit - CSB-EL019162HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Folate Receptor 1, Adult (FOLR1), Human, CLIA Kit - SCF460Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 5.8pg/mL Range 15.6-1,000pg/mL

Fructose 1, 6 bisphosphatase 1 (FBP1), ELISA Kit - MBS7246663 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7244291 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7237914 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7227228 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7224161 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7203940 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7251591 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7244181 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7248037 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7227331 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7231967 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1 (FBP1), ELISA Kit - MBS7201258 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1, 6-bisphosphatase 1, FBP1, ELISA Kit - MBS9307233 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fructose-1,6-bisphosphatase 1, ELISA Kit - MBS282036 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Folate Receptor 1, Adult (FOLR1) - SEF460Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 5.8pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

CLIA Kit for Folate Receptor 1, Adult (FOLR1) - SCF460Hu from Cloud-clone Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.62pg/mL. Range 1.372-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 333.33pg/mL, 111.11pg/mL, 37.04pg/mL, 12.346pg/mL, 4.115pg/mL, 1.372pg/mL

Human FBP1 ELISA Kit (Sandwich ELISA) - LS-F17763 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Rat FBP1 ELISA Kit (Custom ELISA) - LS-F17761 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse FBP1 ELISA Kit (Custom ELISA) - LS-F17762 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Pig FBP1 ELISA Kit (Custom ELISA) - LS-F17764 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

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