| Gene Symbol |
AMBRA1
|
| Entrez Gene |
55626
|
| Alt Symbol |
DCAF3, WDR94
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
autophagy/beclin-1 regulator 1
|
| Other Description |
DDB1 and CUL4 associated factor 3|WD repeat domain 94|activating molecule in BECN1-regulated autophagy protein 1|activating molecule in beclin-1-regulated autophagy
|
| Swissprots |
Q9NXE7 G3V193 A6XN33 Q86XD6 Q9C0C7 D3DQP8 Q9H8Z0
|
| Accessions |
EAW67996 EAW67997 EAW67998 EAW67999 EAW68000 EAW68001 EAW68002 Q9C0C7 AB051523 BAB21827 AK000301 BAA91067 AK023197 BAB14457 AK057896 AK302808 BAG64009 AK304530 BAG65331 AL137611 AL834190 BC045609 AAH45609 BF589843 CA389399 DB070055 DB232750 DQ870924 ABI74670 XM_005253009 XP_005253066 XM_005253011 XP_005253068 XM_005253014 XP_005253071 XM_006718259 XP_006718322 XM_006718260 XP_006718323 XM_011520214 XP_011518516 XM_011520215 XP_011518517 XR_930878 NM_001267782 NP_001254711 NM_001267783 NP_001254712 NM_001300731 NP_001287660 NM_017749 NP_060219
|
| Function |
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, autophagosome {ECO:0000250}. Note=Localizes also to discrete punctae along the ciliary axoneme. {ECO:0000250}.
|