Gene Symbol | AMBRA1 |
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Entrez Gene | 55626 |
Alt Symbol | DCAF3, WDR94 |
Species | Human |
Gene Type | protein-coding |
Description | autophagy/beclin-1 regulator 1 |
Other Description | DDB1 and CUL4 associated factor 3|WD repeat domain 94|activating molecule in BECN1-regulated autophagy protein 1|activating molecule in beclin-1-regulated autophagy |
Swissprots | Q9NXE7 G3V193 A6XN33 Q86XD6 Q9C0C7 D3DQP8 Q9H8Z0 |
Accessions | EAW67996 EAW67997 EAW67998 EAW67999 EAW68000 EAW68001 EAW68002 Q9C0C7 AB051523 BAB21827 AK000301 BAA91067 AK023197 BAB14457 AK057896 AK302808 BAG64009 AK304530 BAG65331 AL137611 AL834190 BC045609 AAH45609 BF589843 CA389399 DB070055 DB232750 DQ870924 ABI74670 XM_005253009 XP_005253066 XM_005253011 XP_005253068 XM_005253014 XP_005253071 XM_006718259 XP_006718322 XM_006718260 XP_006718323 XM_011520214 XP_011518516 XM_011520215 XP_011518517 XR_930878 NM_001267782 NP_001254711 NM_001267783 NP_001254712 NM_001300731 NP_001287660 NM_017749 NP_060219 |
Function | Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, autophagosome {ECO:0000250}. Note=Localizes also to discrete punctae along the ciliary axoneme. {ECO:0000250}. |
AMBRA1 CRISPR/Cas9 KO Plasmid (h) - sc-404108 from Santa Cruz Biotechnology
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AMBRA1 HDR Plasmid (h) - sc-404108-HDR from Santa Cruz Biotechnology
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AMBRA1 Double Nickase Plasmid (h) - sc-404108-NIC from Santa Cruz Biotechnology
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AMBRA1 Double Nickase Plasmid (h2) - sc-404108-NIC-2 from Santa Cruz Biotechnology
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AMBRA1 CRISPR Activation Plasmid (h) - sc-404108-ACT from Santa Cruz Biotechnology
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AMBRA1 CRISPR Activation Plasmid (h2) - sc-404108-ACT-2 from Santa Cruz Biotechnology
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AMBRA1 Lentiviral Activation Particles (h) - sc-404108-LAC from Santa Cruz Biotechnology
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AMBRA1 Lentiviral Activation Particles (h2) - sc-404108-LAC-2 from Santa Cruz Biotechnology
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AMBRA1 siRNA (h) - sc-96257 from Santa Cruz Biotechnology
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AMBRA1 shRNA Plasmid (h) - sc-96257-SH from Santa Cruz Biotechnology
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AMBRA1 shRNA (h) Lentiviral Particles - sc-96257-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3104 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3104 from Sigma-Aldrich
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AMBRA1 siRNA (Human) - CRJ0785 from Cohesion Biosciences
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AMBRA1 - MBS8216659 from MyBioSource
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shRNA set against Human AMBRA1 (NM_017749.3) - SHH235658 from Creative biogene
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Human AMBRA1 siRNA - orb271286 from Biorbyt
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AMBRA1 shRNA Plasmid (Human) - CHJ0785 from Cohesion Biosciences
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AMBRA1 miRNA 3'UTR clone - MiUTR3H-11831 from Creative biogene
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