Gene Symbol |
CXCL17
|
Entrez Gene |
284340
|
Alt Symbol |
DMC, Dcip1, UNQ473, VCC-1, VCC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-X-C motif) ligand 17
|
Other Description |
C-X-C motif chemokine 17|VEGF co-regulated chemokine 1|VEGF coregulated chemokine 1|dendritic cell and monocyte chemokine-like protein
|
Swissprots |
Q6UXB2 A8KAC0
|
Accessions |
Q6UXB2 AK292985 BAF85674 AY358433 AAQ88799 AY598464 AAU04875 BC093946 AAH93946 BC112095 AAI12096 NM_198477 NP_940879
|
Function |
Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774, ECO:0000269|PubMed:17307946}.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up- regulation. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774}.
|